YI WANG1,#, SHANGQI CHEN2,#, PENGCHENG YU1, ZHEHAN BAO1, CAN HU1, YUHANG XIA1, RUOLAN ZHANG1, LI YUAN3,4, HUA RUAN5,*, JIANCHENG SUN6,*
BIOCELL, Vol.47, No.5, pp. 991-1002, 2023, DOI:10.32604/biocell.2023.028587
Abstract Aim: Scavenger receptor class B, type I (SR-BI) is an integral plasma membrane protein that has been reported to be overexpressed in various malignancies, such as renal cancer, breast cancer, and prostate cancer, and is an independent prognostic factor. However, the clinical value and expression of SR-BI in GC are unknown. Our research aimed to explore the role of SR-BI in combination with immune markers as a diagnostic and prognostic marker for gastric cancer (GC). Methods: GC tissues, paracancerous tissues, and clinicopathological data of 149 patients were collected. The expression level of SR-BI, Tumor-infiltrating lymphocytes (TILs), and PD-L1 were evaluated… More >
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