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  • Open Access

    ARTICLE

    Lymphoceles: impact on kidney transplant recipients, graft, and healthcare system

    Emily Nguyen1, Michelle Minkovich1, Olusegun Famure1, Yanhong Li1, Anand Ghanekar1,2, Markus Selzner1,2,*, S. Joseph Kim1,3,*, Jason Y. Lee1,4

    Canadian Journal of Urology, Vol.28, No.5, pp. 10848-10857, 2021

    Abstract Introduction: Following kidney transplantation, lymphoceles can impact patient and graft outcomes, while resulting in significant hospital resource utilization. We aimed to characterize the incidence, risk factors, outcomes, and clinical management of lymphoceles among kidney transplant recipients and review impact on health system utilization at a high-volume center.
    Materials and methods: We conducted a single-center, observational cohort study on adults transplanted between January 1, 2005 and December 31, 2017. Incidence, risk factors, and clinical outcomes were assessed using the Kaplan-Meier product-limit method, multivariable logistic regression model, and Cox proportional hazards model, respectively.
    Results: Lymphoceles developed in 72 of 1881… More >

  • Open Access

    REVIEW

    Ureteroscopic evaluation and treatment of benign essential hematuria: a systematic review

    Nicholas N. Tadros1, Michael J. Conlin2

    Canadian Journal of Urology, Vol.28, No.1, pp. 10510-10515, 2021

    Abstract Introduction: The advent of ureteroscopy has revolutionized the treatment many urologic diseases, including benign essential hematuria. This systematic review examines the treatment of benign essential hematuria (BEH) with ureteroscopic interventions.
    Materials and methods: We performed a systematic review of the literature from 1977 to May 2020. We included studies that evaluated the use of ureteroscopy to diagnose or treat BEH. Demographics, follow up, findings, treatment method and success rate were extracted from each identified paper. Quality analysis was performed independently by both authors.
    Results: Our search resulted in 587 articles. Fifteen of these studies met inclusion criteria and… More >

  • Open Access

    ARTICLE

    MODELING OF THE HEAT TRANSFER IN A SUPERCRITICAL CO2/DME MIXTURE FLOWING IN COOLED HELICALLY COILED TUBES

    Yan Chena , Qingxin Bab,*, Xuefang Lib

    Frontiers in Heat and Mass Transfer, Vol.16, pp. 1-9, 2021, DOI:10.5098/hmt.16.18

    Abstract The heat transfer of supercritical CO2/DME mixtures was modeled in this study for a mass ratio of 95/5 for cooling in horizontal helically coiled tubes. The CO2/DME heat transfer coefficient was higher in the high-temperature zone than with pure CO2. The heat transfer of CO2/DME (95/5) was predicted for various mass fluxes, heat fluxes and pressures. The CO2/DME heat transfer coefficient increased with the mass flux due to the increased turbulent diffusion, and first increased but then decreased with the heat flux. The peak heat transfer coefficient of CO2/DME shifted toward the high-temperature region as the operating pressure… More >

  • Open Access

    ARTICLE

    A NUMERICAL AND EXPERIMENTAL STUDY OF THE EFFECT OF USING PERSONAL VENTILATION SYSTEMS ON INDOOR AIR QUALITY IN OFFICE ROOMS

    Hussien Aziz Saheb,*, Ala'a Abbas Mahdi, Qusay Rasheed Al-amir

    Frontiers in Heat and Mass Transfer, Vol.16, pp. 1-15, 2021, DOI:10.5098/hmt.16.9

    Abstract In this study, indoor air quality and thermal comfort were investigated for two persons sitting inside an office room of dimensions (3×2.5×2.5m). The office room is equipped with personal ventilation systems positioned 50 cm from the person's face. These systems are characterized by the ability to change the rates of airflow (ATD). Experimental studies and results were conducted on a thermal manikin that simulates the human body in a sitting position, and the results are compared with CFD analysis using the k-epsilon and the RNG turbulent models. The experimental study focused on measuring the speed… More >

  • Open Access

    ARTICLE

    NUMERICAL THERMAL STUDY OF HEAT TRANSFER ENHANCEMENT IN LAMINAR-TURBULENT TRANSITION FLOW THROUGH ABSORBER PIPE OF PARABOLIC SOLAR TROUGH COLLECTOR SYSTEM

    Marwa M. Ibrahima,*, Mohamed Mahran Kasemb,c

    Frontiers in Heat and Mass Transfer, Vol.17, pp. 1-11, 2021, DOI:10.5098/hmt.17.20

    Abstract Currently electricity generation technologies by thermal energy conversions become strong demand. The objective of this paper is to present a novel thermal study of absorber/receiver circular pipe of parabolic trough solar collector system for laminar and turbulent (k-ɛ model) fluids flow as well as two-dimensional numerical simulation is performed using CFD ANSYS FLUENT software. Significant improvements in heat transfer and velocity were discovered; the pattern of temperature distribution over the pipe absorber was displayed, and velocity vectors, pressure contours, and temperature contours were studied. The impact of increasing the heat flux towards the pipe wall More >

  • Open Access

    ARTICLE

    LITHIUM-ION BATTERY FIRE SUPPRESSION USING WATER MIST SYSTEMS

    Matt Ghijia,*, Ian Burchb, Brigitta Suendermannb, Grant Gambleb, Vasily Novozhilov a, Paul Josepha, Khalid Moinuddina

    Frontiers in Heat and Mass Transfer, Vol.17, pp. 1-8, 2021, DOI:10.5098/hmt.17.13

    Abstract Lithium-ion batteries (LiBs) have superior energy density and lifetime compared to battery technologies such as lead acid. Despite the widespread application of LiBs in energy storage systems, electronic devices, aerospace and the automotive industry, they present a fire risk. In this study, experiments were conducted to characterize the thermal behavior of the electrolyte (as the main contributor to LiB fires) using a cone calorimeter; investigate the interactions of water mist and a Bunsen burner, as a precursor to examining the effectiveness of a water mist suppression system in extinguishing a LiB fire. In the present… More >

  • Open Access

    ARTICLE

    Lactate Maintains BCR/Abl Expression and Signaling in Chronic Myeloid Leukemia Cells Under Nutrient Restriction

    Angela Silvano*†1, Giulio Menegazzi*1, Silvia Peppicelli*1, Caterina Mancini*, Alessio Biagioni*, Alessandro Tubita*, Ignazia Tusa*, Jessica Ruzzolini*, Matteo Lulli*, Elisabetta Rovida*, Persio Dello Sbarba*

    Oncology Research, Vol.29, No.1, pp. 33-46, 2021, DOI:10.3727/096504022X16442289212164

    Abstract This study was directed to deepen the effects of nutrient shortage on BCR/Ablprotein expression and signaling in chronic myeloid leukemia (CML) cells. The backbone of the study was cell culture in medium lacking glucose, the consumption of which we had previously shown to drive BCR/Ablprotein suppression, and glutamine, the other main nutrient besides glucose. In this context, we focused on the role of lactate, the main by-product of glucose metabolism under conditions of rapid cell growth, in particular as a modulator of the maintenance of CML stem/progenitor cell potential, a crucial determinant of disease course More >

  • Open Access

    REVIEW

    Applications of CRISPR-Cas System in Tumor Biology

    Mengdan Ma1,2, Yuchen Liu1,*, Weiren Huang1,*

    Oncologie, Vol.23, No.4, pp. 463-492, 2021, DOI:10.32604/oncologie.2022.019415 - 31 December 2021

    Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas system, which is an RNA-guided nuclease system, plays an important role in the adaptive immune response of bacteria, and it is a rapidly developing gene editing technology. It has been widely used in a variety of cells, microorganisms, plants, and animals. This technique has helped to overcome the limitations of previous gene editing methods, and it has promoted the development of synthetic biology, genetics, and proteomics. The ability of the CRISPR-Cas system to modify the genetic components of a system has led to various practical applications, such… More >

  • Open Access

    REVIEW

    The Current Status of Chlorin e6-Based Nanoscale Delivery Systems for Cancer Therapy

    Zhengyi Li1,2,3, Lihua Qiu1,2,3,*

    Oncologie, Vol.23, No.4, pp. 515-531, 2021, DOI:10.32604/oncologie.2021.019856 - 31 December 2021

    Abstract Improving the effectiveness of cancer treatment has become a central concern for the public. In recent years, in order to maximize the efficiency of cancer treatment, photodynamic therapy (PDT) and sonodynamic therapy (SDT) have received widespread attention. Chlorin e6 (Ce6) is a fluorescent dye with strong optical properties and excellent photoconversion efficiency under near-infrared light irradiation, which has been widely used in PDT in recent decades due to its superior antitumor ability. Of note, Ce6 can be used as a sonosensitizer for SDT, which generates large amounts of reactive oxygen species (ROS) for tumor treatment More >

  • Open Access

    ARTICLE

    Design of Cybersecurity Threat Warning Model Based on Ant Colony Algorithm

    Weiwei Lin1,2,*, Reiko Haga3

    Journal on Big Data, Vol.3, No.4, pp. 147-153, 2021, DOI:10.32604/jbd.2021.017299 - 20 December 2021

    Abstract In this paper, a cybersecurity threat warning model based on ant colony algorithm is designed to strengthen the accuracy of the cybersecurity threat warning model in the warning process and optimize its algorithm structure. Through the ant colony algorithm structure, the local global optimal solution is obtained; and the cybersecurity threat warning index system is established. Next, the above two steps are integrated to build the cybersecurity threat warning model based on ant colony algorithm, and comparative experiment is also designed. The experimental results show that, compared with the traditional qualitative differential game-based cybersecurity More >

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