MARÍA G. FLORES-SÁNCHEZ1,*, ROBERTO OLAYO2, J. MORALES-CORONA2, ATLÁNTIDA M. RAYA-RIVERA3, DIEGO R. ESQUILIANO-RENDÓN3
BIOCELL, Vol.46, No.3, pp. 829-836, 2022, DOI:10.32604/biocell.2022.016988
Abstract This article presents the construction of scaffolds composed of polylactic acid (PLA) with different concentrations of hydroxyapatite (HA) by electrospinning, which were superficially modified with polypyrrole (PPy/I) by plasma polymerization. A preliminary study was conducted of the biological and mechanical behavior of the scaffolds when they were implanted in the back of rabbits for 30 days; bone cells differentiated from mesenchymal stem cells (MSCs) were used. The bone cell and scaffold structures were characterized by histological, immunohistochemical, and mechanical stress tests. Hematoxylin–eosin staining showed good tissue conformation. The immunohistochemical tests highlighted the presence of the main bone tissue proteins, such… More >
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