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  • Open Access

    ARTICLE

    Adjuvant Chemotherapy Following Surgical Resection Improves Survival in Patients With Early Stage Small Cell Lung Cancer

    Yuanshan Yao, Yinjie Zhou, Zhenhua Yang, Hongbo Huang, Haibo Shen

    Oncology Research, Vol.27, No.2, pp. 203-210, 2019, DOI:10.3727/096504018X15202953107093

    Abstract The purpose of this study was to determine the effects of resection coupled with standard chemotherapy on the survival prognosis of patients with early stage small cell lung carcinoma (SCLC). Patients (n=110) with mediastinal lymph node-negative SCLC were enrolled in this study. The baseline clinical data of patients with surgery were retrospectively reviewed. Overall survival (OS) and progression-free survival (PFS) were measured by Kaplan–Meier and log-rank test analyses. Ninety-eight patients received mediastinoscopy biopsy, and pulmonary lobectomy or sublobar resection, and 67 patients underwent adjuvant chemotherapy after pulmonary lobectomy. Adjuvant chemotherapy after surgical intervention was associated with longer OS (median OS:… More >

  • Open Access

    ARTICLE

    Quand et avec quelles conséquences opérer une tumeur neuroendocrine du pancréas ou du grêle ?*
    When to Operate and What Are the Consequences of a Surgical Resection of a Neuroendrocine Tumour in the Pancreas or Small Bowel

    E. Hain, J. Gharios, R. Sindayigaya, S. Gaujoux

    Oncologie, Vol.21, No.2, pp. 91-96, 2019, DOI:10.3166/onco-2019-0048

    Abstract Neuroendocrine tumors (NET) are rare and can occur in all parts of the digestive tract. They can be functional or non-functional. All patients presenting NET should be discussed for the surgical management within the RENATEN tumor board. For sporadic pancreatic NET, surgery is recommended for non-functional lesion >2 cm in size and/or associated with ductal dilatation. For non-aggressive tumor, parenchyma-sparing surgery should be preferred to avoid exocrine and endocrine pancreatic insufficiency. For small bowel NET, surgery must always be considered to avoid complications such as small bowel obstruction. Lymphadenectomy must include at least 8 noded. Surgery must avoid short bowel… More >

  • Open Access

    ARTICLE

    Outcomes in patients with cor triatriatum sinister

    Margaret M. Fuchs1, Heidi M. Connolly1, Sameh M. Said2, Alexander C. Egbe1

    Congenital Heart Disease, Vol.13, No.4, pp. 628-632, 2018, DOI:10.1111/chd.12624

    Abstract Objective: To describe outcomes in patients with cor triatriatum sinister (CTS).
    Design: Retrospective review of patients with CTS followed at Mayo Clinic Rochester from 1990 to 2016. Clinical notes, operative reports, and baseline imaging studies were reviewed including echocardiogram, magnetic resonance imaging, computed tomography, and cardiac catheterization.
    Results: Fifty-seven patients (median age 34 years; men 32 (56%)) were enrolled. Definitive or suspected CTS diagnosis was made by transthoracic echocardiogram in 41 (72%) patients, and additional multimodality imaging was required in 39 (68%) patients. Of these 57 patients, initial diagnosis was made in adulthood in 35 (61%) patients, and 33 of… More >

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