T. Ganier, J. Hu, A. Pizzi^*

Journal of Renewable Materials, Vol.1, No.1, pp. 79-82, 2013, DOI:10.7569/JRM.2012.634101

Abstract Linear vibration welding of extractive rich Paduk wood from central Africa containing a high proportion of a native mixture of water-insoluble extractives, or of low water solubility, has been shown to yield joints of much upgraded water resistance. This has been shown to be due to the protecting infl uence the extractives from the wood itself has on the welded interphase, due to their inherent water repellence. Joints of unusually high percentage wood failure but modest strength were obtained; Paduk wood brittleness apparently yielding weld line strengths always higher than that of the surrounding wood itself. This indicated that Paduk… More >

Jutarat Tanasansuttiporn¹, Maliwan Oofuvong^1,*, Wirat Wasinwong¹, Voravit Chittithavorn², Pongsanae Duangpakdee², Jirayut Jarutach³, Qistina Yunuswangsa¹

Congenital Heart Disease, Vol.17, No.3, pp. 245-267, 2022, DOI:10.32604/chd.2022.021778

Abstract Background: Studies on predictors of health-related quality of life (HRQOL) in pediatric patients with cyanotic heart disease who are waiting for the next stage and those who have undergone total repair are scarce. Therefore, we aimed to identify such predictors in children who received the modified Blalock–Taussig shunt (MBTS) and those who underwent total repair. Methods: In this historical cohort and concurrent follow-up study, data of children who underwent MBTS at the age of 0–3 years between January 2005 and December 2016 at a super-tertiary care hospital in Southern Thailand were obtained. Children who were alive in December 2017 were… More > Graphic Abstract

MOHAMED AGHYAD AL KABBANI^1,2, GILBERT WUNDERLICH^3,4, CHRISTOPH KöHLER⁵, HANS ZEMPEL^1,2,*

BIOCELL, Vol.46, No.4, pp. 847-853, 2022, DOI:10.32604/biocell.2022.018144

Abstract Tauopathies comprise a spectrum of genetic and sporadic neurodegenerative diseases mainly characterized by the presence of hyperphosphorylated TAU protein aggregations in neurons or glia. Gene therapy, in particular adeno-associated virus (AAV)-based, is an effective medical approach for difficult-to-treat genetic diseases for which there are no convincing traditional therapies, such as tauopathies. Employing AAV-based gene therapy to treat, in particular, genetic tauopathies has many potential therapeutic benefits, but also drawbacks which need to be addressed in order to successfully and efficiently adapt this still unconventional therapy for the various types of tauopathies. In this Viewpoint, we briefly introduce some potentially treatable… More >

Sibao Wang, Silin Pan^*, Gang Luo, Zhixian Ji, Na Liu

Congenital Heart Disease, Vol.17, No.1, pp. 45-60, 2022, DOI:10.32604/CHD.2022.016332

Abstract The aim of this study was to perform a systematic review and meta-analysis to evaluate the safety and efficacy of ductus arteriosus stent (DAS) compared with surgical systemic-pulmonary artery shunt (SPS) in patients with ductal-dependent pulmonary blood flow. A literature search was conducted in PubMed, Embase, and the Cochrane Library databases from their inception to December 2020. Two reviewers independently screened the articles, evaluated the quality of the articles, and collected the data. Meta-analyses were conducted using fixed and random effects models. We used the I-square (I² ) test to examine heterogeneity and the funnel plot Egger’s test was used… More >

Hosam F. El-Sofany^1,2,*, Samir A. El-Seoud³

Computer Systems Science and Engineering, Vol.40, No.1, pp. 389-404, 2022, DOI:10.32604/csse.2022.018619

Abstract Ubiquitous computing supports U-learning to develop and implement a new educational environment that provides effective and interactive learning to students wherever they are. This study aims to present a qualitative evaluation for using U-learning instead of traditional education to avoid the spread of the Coronavirus pandemic. The authors introduce a UTAUT (Unified Theory of Acceptance and Use of Technology) model to assess the capability of the given factors that are expected to affect the learners’ intention and behavior for accepting the U-learning technology for full E-learning. The research study shows a promising impact on the use of U-learning apps for… More >

NARAYANAN NAMPOOTHIRI V. P.¹, VIGNESH SUNDARARAJAN¹, PALLAVI DAN¹, G. DEVANAND VENKATASUBBU^2,*, SAHABUDEEN SHEIK MOHIDEEN^1,*

BIOCELL, Vol.45, No.5, pp. 1251-1262, 2021, DOI:10.32604/biocell.2021.015090

Abstract Alzheimer’s disease (AD) is one of the most common forms of dementia. Cognitive dysfunction and memory loss are the two main clinical symptoms of AD. Drosophila melanogaster models of AD, which are based on overexpression of human amyloid β (Aβ) or human tau (hTau) protein, have been used to study the mechanism underlying AD and to screen potential therapeutic compounds. Drugs that are currently available for AD provide only symptomatic relief. Huge unmet medical needs exists to slow, stop, or reverse the progression of AD. Thymoquinone (TQ) is an active ingredient isolated from Nigella sativa (NS) and possesses various pharmacological… More >

Siraphop Thapmongkol^1,*, Jarun Sayasathid¹, Jessada Methrujpanont², Kanthachat Thatsakorn¹, Worawan Jittham³, Suwanna Puitm⁴, Methiniwiran Thapmongkol⁵, Jule Namchaisiri⁶

Congenital Heart Disease, Vol.16, No.5, pp. 433-441, 2021, DOI:10.32604/CHD.2021.015770

Abstract Background: The surgical outcomes of tetralogy of Fallot (TOF) have evolved dramatically and have resulted in lower mortality rate. Currently, the many cardiac centers have a trend to early single-stage complete repair more than a staged repair. However, the patients who have an early primary repair were required transannular patch augmentation of a pulmonary valve frequently. This effect has been developed a chronic pulmonary insufficiency may lead to right ventricular dilation, dysfunction. In this era, the aim of treatment of TOF is attempted to preserve pulmonary valve annulus for prevent right ventricular dysfunction in the future. The systemic to pulmonary… More >

Pierre-Guillaume Poureau^1,2,*, Jean-Philippe Metges²

Oncologie, Vol.23, No.1, pp. 47-59, 2021, DOI:10.32604/Oncologie.2021.15525

Abstract Immunotherapy for digestive cancers is booming and for the first time an immune checkpoint inhibitor has been granted marketing authorization for the treatment of digestive cancer. In order to better understand the mecanism of action of these treatments, their adverse events and the escape mecansim, it is necessary to know the fundamentals of cancer immunology. The innate and adaptive immune system allows the elimination of cancer cells by direct non-specific cytotoxicity (Natural Killer cells), by the development of an adaptive cell-mediated response (dendritic cells becoming antigen presenting cells, allowing the differentiation of lymphocytes naive in CD4 and CD8 T lymphocytes)… More >

Malik Khlaif Gharaibeh¹, Natheer Khlaif Gharaibeh^2,*, Mohammad Ayoub Khan³, Waleed Abdel karim Abu-ain⁴, Musab Kasim Alqudah²

Computer Systems Science and Engineering, Vol.37, No.2, pp. 187-202, 2021, DOI:10.32604/csse.2021.014902

Abstract This article examines the main variables that influence the intention to use Augmented Reality (AR) applications in the tourism sector in Jordan. The study model has been constructed based on the unified theory of acceptance and the use of technology2 (UTAUT2), by incorporating a new construct (aesthetics) to explore the usage intention of Mobile Augmented Reality in Tourism (MART). A questionnaire was used and distributed to a sample of 450 participants. Data were analyzed using the Smart PLS version 3.0. for testing 12 hypotheses. 29 measurement items were carefully reviewed based on previous studies that were selected to assess the… More >

Nunzia Borrelli^1,2, Jolanda Sabatino^1,3, Martina Avesani^1,4, Josefa Paredes¹, Manjit Josen¹, Alain Fraisse¹, Paolo Guccione², Guido Michielon¹, Giovanni Di Salvo^1,4,*

Congenital Heart Disease, Vol.16, No.1, pp. 27-37, 2021, DOI:10.32604/CHD.2021.012526

Abstract Background: Still little is known about the impact on right ventricle function of the 2 main approaches to Norwood palliation in Hypoplastic left heart syndrome, the right ventricle-pulmonary artery shunt (RVPAS) and the modified Blalock-Taussig shunt (mBTS). Methods: The cohort included 27 patients with Hypoplastic left heart syndrome (10 in the mBTS group, 17 in the RVPAS group). Longitudinal strain, tricuspid annulus peak systolic excursion and fractional area change were evaluated before Norwood and in four different breakpoints in the steady-state after Norwood procedure (30-days, 90-days, 140-days and 200-days after Norwood). Results: No significant differences were found in all standard… More >