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  • Open Access

    ARTICLE

    Mesenchymal stem cells are more effective than captopril in reverting cisplatin-induced nephropathy

    Entsar A. SAAD1, Reda S. EL-DEMERDASH2, Eman M. ABD EI-FATTAH1

    BIOCELL, Vol.43, No.2, pp. 73-80, 2019, DOI:10.32604/biocell.2019.07020

    Abstract Cisplatin is a powerful anticancer drug but its nephrotoxic effects limit its clinical use. We aimed to evaluate the effect of mesenchymal stem cells (MSCs) injection or of captopril to counteract the cisplatin-induction of nephropathy. MSCs isolation, preparation and tracking, transforming growth factor-β (TGF-β) and interleukin-10 (IL-10) expressions, kidney function tests, oxidative stress state, and histological examinations were done. Cisplatininduced nephropathy was indicated biochemically and confirmed histopathologically. MSCs treatment showed normal kidney architecture, and significantly decreased oxidative stress and TGF-β while increased IL-10 and improved kidney function tests. Rats treated with cisplatin + captopril showed noticeable kidney histopathological changes. Superior… More >

  • Open Access

    ARTICLE

    Extraction and Characterization of Aucoumea klaineana Pierre (Okoume) Extractives

    Engozogho Anris Starlin Peguy1,2, Bikoro Bi Athomo Arsene1,2, Vidal Marcia5, Denaud Louis4, Safou Tchiama Rodrigue2,3, Charrier Bertrand1

    Journal of Renewable Materials, Vol.7, No.6, pp. 517-522, 2019, DOI:10.32604/jrm.2019.04051

    Abstract In order to promote convenient strategies for the utilization of wood wastes from aucoumea klaineana pierre (okoume) timber industry, various chemical analysis were carried out on samples from different origins. Total extractives content of the bark, sapwood and heartwood of okoume were evaluated. thermogravimetric analyses were performed and the stiasny number was calculated. it was found that the bark was richer in fatty acid of high molecular weight while the sapwood was rich in fatty acid of low molecular weight. the condensed tannins content varied according to the origin and the part of the tree. these new findings should be… More >

  • Open Access

    ARTICLE

    Investigation of CNSL-Based Hybrid Sol in Conventional Polymeric Material

    Dinesh Balgude, Anagha Sabnis*

    Journal of Renewable Materials, Vol.4, No.2, pp. 146-157, 2016, DOI:10.7569/JRM.2015.634117

    Abstract The performance properties of conventional polymeric material have been investigated by modifying it with cashew nut shell liquid (CNSL) derived hybrid precursor. The synthesis of hybrid material involved formation of maleic anhydride adduct of CNSL followed by silane modifi cation and subsequent hydrolysis and condensation with tetra ethyl orthosilicate. The developed hybrid material was characterized by a number of instrumental techniques like FT-IR, 1H-NMR and 13C-NMR, as reported in our earlier work. In the present work, we have investigated the effect of CNSL-based hybrid material on the performance properties of conventional alkyd-melamine formaldehyde-based stoving system. The synthesized material was used… More >

  • Open Access

    ARTICLE

    In Vitro Measurement and Calculation of Drag Force on Iliac Limb Stentgraft in a Compliant Arterial Wall Model

    A. Sinha Roy*, K. West, R. S. Rontala1, R. K. Greenberg2, R. K. Banerje1,‡

    Molecular & Cellular Biomechanics, Vol.4, No.4, pp. 211-226, 2007, DOI:10.3970/mcb.2007.004.211

    Abstract Interventional treatment of aortic aneurysms using endovascular stentgrafting is a minimally invasive technique. Following device implantation, transient drag forces act on the stentgraft. When the drag force exceeds the fixation force, complications like stentgraft migration, endoleaks and stentgraft failure occur. In such a scenario the device becomes unstable, causing concern over the long-term durability of endovascular repairs. The objective of this study is: 1) to measure the drag force on iliac limb stentgraft, having a distal diameter that is half the size of the proximal end, in an in vitro experiment; 2) to calculate the drag force using blood flow--compliant… More >

  • Open Access

    ARTICLE

    Credit Card Fraud Detection Based on Machine Learning

    Yong Fang1, Yunyun Zhang2, Cheng Huang1,*

    CMC-Computers, Materials & Continua, Vol.61, No.1, pp. 185-195, 2019, DOI:10.32604/cmc.2019.06144

    Abstract In recent years, the rapid development of e-commerce exposes great vulnerabilities in online transactions for fraudsters to exploit. Credit card transactions take a salient role in nowadays’ online transactions for its obvious advantages including discounts and earning credit card points. So credit card fraudulence has become a target of concern. In order to deal with the situation, credit card fraud detection based on machine learning is been studied recently. Yet, it is difficult to detect fraudulent transactions due to data imbalance (normal and fraudulent transactions), for which Smote algorithm is proposed in order to resolve data imbalance. The assessment of… More >

  • Open Access

    ARTICLE

    Effects of TGO Roughness on Indentation Response of Thermal Barrier Coatings

    Taotao Hu1, gping Shen1,2

    CMC-Computers, Materials & Continua, Vol.17, No.1, pp. 41-58, 2010, DOI:10.3970/cmc.2010.017.041

    Abstract In this paper, an axisymmetric indentation model is set up to calculate the effects of the roughness of the thermally grown oxide (TGO) layer, which was modeled as a sinusoidal wave, on the indentation response of the thermal barrier coatings. It is found that the amplitude, wavelength, and thickness of the thermally grown oxide layer have obvious influences on the indentation response, while the effect of the indenter position can be neglected. In the top coating layer, residual stress mainly occurs below the indenter and around the nearest two peaks of the thermally grown oxide layer to the indenter. Only… More >

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