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  • Open Access

    ABSTRACT

    From Cell Mechanobiology to Mechanomedicine: A Research Path Inspired by Fung - Dedicated to Prof. YC Fung on the Occasion of His Centennial Birthday

    Ning Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 21-21, 2019, DOI:10.32604/mcb.2019.07550

    Abstract Decades ago YC Fung proposed that mechanical stress could have substantial impacts on remodeling and growth of living tissues. Fung also proposed the concept of residual stress in blood vessels and quantified residual stress in excised arteries [1]. However, how stress influences cell and tissue functions remains elusive. At the cellular level, we have quantified myosin II mediated pre-existing tensile stress (prestress) in living cells and demonstrated that the prestress (the endogenous cytoskeletal tension) regulates cell stiffness, gene expression, and long-distance stress propagation in the cytoplasm to activate enzymes [2]. The prestress even impacts on force-induced direct chromatin stretching and… More >

  • Open Access

    ABSTRACT

    Biomechanics and Yuan-Cheng (Y. C.) Fung: A Special Tribute on His 100th Birthday

    Savio L-Y. Woo1,*, Peter C-Y Chen2

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 1-2, 2019, DOI:10.32604/mcb.2019.07631

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Modeling and Analysis of Novel Multilevel Inverter Topology with Minimum Number of Switching Components

    V. Thiyagarajan1, P. Somasundaram2

    CMES-Computer Modeling in Engineering & Sciences, Vol.113, No.4, pp. 461-473, 2017, DOI:10.3970/cmes.2017.113.461

    Abstract This paper proposes a novel single phase symmetrical and asymmetrical type extendable multilevel inverter topology with minimum number of switches. The basic circuit of the proposed inverter topology consist of four dc voltage sources and 10 main switches which synthesize 9-level output voltage during symmetrical operation and 17-level output voltage during asymmetrical operation. The comparison between the proposed topology with conventional and other existing inverter topologies is presented in this paper. The advantages of the proposed inverter topology includes minimum switches, less harmonic distortion and minimum switching losses. The performance of the proposed multilevel inverter topology has been analyzed in… More >

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