Oncology Research Editorial Office

Oncology Research, Vol.32, No.11, pp. 1813-1813, 2024, DOI:10.32604/or.2024.056888 - 16 October 2024

Abstract This article has no abstract. More >

SULING XU¹, XIAO LI², WENXUE MA^3,*

Oncology Research, Vol.32, No.11, pp. 1701-1708, 2024, DOI:10.32604/or.2024.055161 - 16 October 2024

Abstract The environment surrounding a tumor, known as the tumor microenvironment (TME), plays a role in how cancer progresses and responds to treatment. It poses both challenges and opportunities for improving cancer therapy. Recent progress in understanding the TME complexity and diversity has led to approaches for treating cancer. This perspective discusses the strategies for targeting the TME, such as adjusting networks using extracellular vesicles to deliver drugs and enhancing immune checkpoint inhibitors (ICIS) through combined treatments. Furthermore, it highlights adoptive cell transfer (ACT) therapies as an option for tumors. By studying how components of the More >

LICHEN XU^1,2, PAN ZHANG^3,*, GUIQI ZHANG², ZHAOLIANG SHEN⁴, XIZHUANG BAI^1,3,*

Oncology Research, Vol.32, No.11, pp. 1777-1789, 2024, DOI:10.32604/or.2024.047704 - 16 October 2024

Abstract Background: Osteosarcoma (OS), recognized as the predominant malignant tumor originating from bones, necessitates an in-depth comprehension of its intrinsic mechanisms to pinpoint novel therapeutic targets and enhance treatment methodologies. The role of fat mass and obesity-associated (FTO) in OS, particularly its correlation with malignant traits, and the fundamental mechanism, remains to be elucidated. Materials and Methods: 1. The FTO expression and survival rate in tumors were analyzed. 2. FTO in OS cell lines was quantified utilizing western blot and PCR. 3. FTO was upregulated and downregulated separately in MG63. 4. The impact of FTO on the… More >

Suya Li¹, Ying Cao^1,*, Hengyi Ren², Dongsheng Zhu³, Xin Xie¹

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1449-1470, 2024, DOI:10.32604/cmc.2024.056824 - 15 October 2024

Abstract Multi-object tracking (MOT) has seen rapid improvements in recent years. However, frequent occlusion remains a significant challenge in MOT, as it can cause targets to become smaller or disappear entirely, resulting in low-quality targets, leading to trajectory interruptions and reduced tracking performance. Different from some existing methods, which discarded the low-quality targets or ignored low-quality target attributes. LQTTrack, with a low-quality association strategy (LQA), is proposed to pay more attention to low-quality targets. In the association scheme of LQTTrack, firstly, multi-scale feature fusion of FPN (MSFF-FPN) is utilized to enrich the feature information and assist… More >

Tongan Yu¹, Yali Xue^1,*, Yiming He¹, Shan Cui², Jun Hong²

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1235-1250, 2024, DOI:10.32604/cmc.2024.056075 - 15 October 2024

Abstract With the rapid development of deep learning-based detection algorithms, deep learning is widely used in the field of infrared small target detection. However, well-designed adversarial samples can fool human visual perception, directly causing a serious decline in the detection quality of the recognition model. In this paper, an adversarial defense technology for small infrared targets is proposed to improve model robustness. The adversarial samples with strong migration can not only improve the generalization of defense technology, but also save the training cost. Therefore, this study adopts the concept of maximizing multidimensional feature distortion, applying noise… More >

Juanling Liang¹, Wenguang Luo^1,2,*, Yongxin Qin¹

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1009-1027, 2024, DOI:10.32604/cmc.2024.055883 - 15 October 2024

Abstract An improved RRT* algorithm, referred to as the AGP-RRT* algorithm, is proposed to address the problems of poor directionality, long generated paths, and slow convergence speed in multi-axis robotic arm path planning. First, an adaptive biased probabilistic sampling strategy is adopted to dynamically adjust the target deviation threshold and optimize the selection of random sampling points and the direction of generating new nodes in order to reduce the search space and improve the search efficiency. Second, a gravitationally adjustable step size strategy is used to guide the search process and dynamically adjust the step-size to… More >

Kelan Ren, Facheng Yan, Honghua Chen, Wen Jiang, Bin Wei, Mingshu Zhang^*

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 789-807, 2024, DOI:10.32604/cmc.2024.055624 - 15 October 2024

Abstract The task of cross-target stance detection faces significant challenges due to the lack of additional background information in emerging knowledge domains and the colloquial nature of language patterns. Traditional stance detection methods often struggle with understanding limited context and have insufficient generalization across diverse sentiments and semantic structures. This paper focuses on effectively mining and utilizing sentiment-semantics knowledge for stance knowledge transfer and proposes a sentiment-aware hierarchical attention network (SentiHAN) for cross-target stance detection. SentiHAN introduces an improved hierarchical attention network designed to maximize the use of high-level representations of targets and texts at various… More > Graphic Abstract

Mustafa Mohammed Alhassow^1,*, Oguz Ata², Dogu Cagdas Atilla¹

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 749-771, 2024, DOI:10.32604/cmc.2024.055592 - 15 October 2024

Abstract This study investigates robot path planning for multiple agents, focusing on the critical requirement that agents can pursue concurrent pathways without collisions. Each agent is assigned a task within the environment to reach a designated destination. When the map or goal changes unexpectedly, particularly in dynamic and unknown environments, it can lead to potential failures or performance degradation in various ways. Additionally, priority inheritance plays a significant role in path planning and can impact performance. This study proposes a Conflict-Based Search (CBS) approach, introducing a unique hierarchical search mechanism for planning paths for multiple robots.… More >

Futai Liang^1,2, Xin Chen^1,*, Song He¹, Zihao Song¹, Hao Lu³

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1101-1121, 2024, DOI:10.32604/cmc.2024.055326 - 15 October 2024

Abstract In the application of aerial target recognition, on the one hand, the recognition error produced by the single measurement of the sensor is relatively large due to the impact of noise. On the other hand, it is difficult to apply machine learning methods to improve the intelligence and recognition effect due to few or no actual measurement samples. Aiming at these problems, an aerial target recognition algorithm based on self-attention and Long Short-Term Memory Network (LSTM) is proposed. LSTM can effectively extract temporal dependencies. The attention mechanism calculates the weight of each input element and… More >

Fahim Nasir¹, Abdulghani Ali Ahmed^1,*, Mehmet Sabir Kiraz¹, Iryna Yevseyeva¹, Mubarak Saif²

CMC-Computers, Materials & Continua, Vol.81, No.1, pp. 1703-1728, 2024, DOI:10.32604/cmc.2024.055192 - 15 October 2024

Abstract Integrating machine learning and data mining is crucial for processing big data and extracting valuable insights to enhance decision-making. However, imbalanced target variables within big data present technical challenges that hinder the performance of supervised learning classifiers on key evaluation metrics, limiting their overall effectiveness. This study presents a comprehensive review of both common and recently developed Supervised Learning Classifiers (SLCs) and evaluates their performance in data-driven decision-making. The evaluation uses various metrics, with a particular focus on the Harmonic Mean Score (F-1 score) on an imbalanced real-world bank target marketing dataset. The findings indicate… More >