MARÍA ELISA MILLÁN1, MARÍA FERNANDA MARRA1, LEONARDO ANDRÉS SALVARREDI1,2,3, EMILIO FERNANDO LIZARRAGA4,*, LUIS ALBERTO LOPEZ1,*
BIOCELL, Vol.44, No.3, pp. 293-299, 2020, DOI:10.32604/biocell.2020.012342
Abstract The ajenjo, Artemisia mendozana DC. var. mendozana (Asteraceae), grows in the Andean foothills of Mendoza
and San Juan, Argentina, and is used as a medicinal plant for its antispasmodic and antifungal properties. The aim of this
work was to obtain fractions of a chloroform extract of ajenjo leaves and to evaluate the in vitro effects on proliferation,
viability and clonogenicity of B16-F0 melanoma cells. Using a silica gel chromatography column, 120 fractions were
collected and grouped according to the chromatographic profile in 9 main fractions (F1–F9). Their major compounds
identified were: terpenes (F1), terpenes and sesquiterpene lactones (F2–F3), sesquiterpenes (F4–F6)… More >
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