JULIANA A. PORTES1, ROSSIANE C. VOMMARO1, LUCIO AYRES CALDAS2, ERICA S. MARTINS-DUARTE3,*
BIOCELL, Vol.47, No.4, pp. 929-950, 2023, DOI:10.32604/biocell.2023.026629
Abstract Toxoplasma gondii is a protozoan of worldwide distribution and the agent of toxoplasmosis. It is estimated that 30%–50% of the world population could be infected with this parasite. Although the infection in immunocompetent individuals is mostly asymptomatic, the disease in immunosuppressed and pregnant is a risk condition. As a member of the phylum Apicomplexa, T. gondii has an obligatory intracellular lifestyle; therefore, invading a host cell and establishing it inside a parasitophorous vacuole (PV) are mandatories for the survival of this parasite. The construction of a perfect intracellular niche for T. gondii requires the secretion of an arsenal of proteins… More >
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