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    Knockdown of TRIM44 Inhibits the Proliferation and Invasion in Prostate Cancer Cells

    Yuying Tan*, Hanxin Yao, Jinghai Hu, Lingyun Liu§

    Oncology Research, Vol.25, No.8, pp. 1253-1259, 2017, DOI:10.3727/096504017X14854310794561

    Abstract Tripartite motif 44 (TRIM44), a member of the TRIM protein family, has been shown to play a role in tumor development and progression. However, the potential involvement of TRIM44 in prostate cancer has not been fully explored. Therefore, in the present study, we analyzed the expression of TRIM44 in prostate cancer and assessed the role of TRIM44 in the progression of prostate cancer. Our results showed that the expression of TRIM44 was significantly upregulated in human prostate cancer cell lines. In addition, knockdown of TRIM44 significantly inhibited the proliferation, migration, and invasion of prostate cancer More >

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