Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (2)
  • Open Access

    REVIEW

    Omics sciences for cervical cancer precision medicine from the perspective of the tumor immune microenvironment

    GUANTING PANG1,5,#, YAOHAN LI2,5,#, QIWEN SHI3, JINGKUI TIAN5, HANMEI LOU4,5,*, YUE FENG4,5,*

    Oncology Research, Vol.33, No.4, pp. 821-836, 2025, DOI:10.32604/or.2024.053772 - 19 March 2025

    Abstract Immunotherapies have demonstrated notable clinical benefits in the treatment of cervical cancer (CC). However, the development of therapeutic resistance and diverse adverse effects in immunotherapy stem from complex interactions among biological processes and factors within the tumor immune microenvironment (TIME). Advanced omic technologies offer novel insights into a more expansive and thorough layer of the TIME. Furthermore, integrating multidimensional omics within the frameworks of systems biology and computational methodologies facilitates the generation of interpretable data outputs to characterize the clinical and biological trajectories of tumor behavior. In this review, we present advanced omics technologies that More >

  • Open Access

    ARTICLE

    SR-BI expression regulates the gastric cancer tumor immune microenvironment and is associated with poor prognosis

    YI WANG1,#, SHANGQI CHEN2,#, PENGCHENG YU1, ZHEHAN BAO1, CAN HU1, YUHANG XIA1, RUOLAN ZHANG1, LI YUAN3,4, HUA RUAN5,*, JIANCHENG SUN6,*

    BIOCELL, Vol.47, No.5, pp. 991-1002, 2023, DOI:10.32604/biocell.2023.028587 - 10 April 2023

    Abstract Aim: Scavenger receptor class B, type I (SR-BI) is an integral plasma membrane protein that has been reported to be overexpressed in various malignancies, such as renal cancer, breast cancer, and prostate cancer, and is an independent prognostic factor. However, the clinical value and expression of SR-BI in GC are unknown. Our research aimed to explore the role of SR-BI in combination with immune markers as a diagnostic and prognostic marker for gastric cancer (GC). Methods: GC tissues, paracancerous tissues, and clinicopathological data of 149 patients were collected. The expression level of SR-BI, Tumor-infiltrating lymphocytes (TILs),… More >

Displaying 1-10 on page 1 of 2. Per Page