PRIYANKA THAKUR1, REENA V. SAINI2,3,*, ANIL K. CHHILLAR4, NEERAJ K. SAINI5, VIJAY KUMAR THAKUR6, SAMARJEET SINGH SIWAL7, ADESH K. SAINI2,3,*
BIOCELL, Vol.46, No.2, pp. 309-324, 2022, DOI:10.32604/biocell.2022.016916
Abstract Breast cancer, also recognized as the principal cause of cancer-related deaths among women, is the second most familiar and prevalent form of cancer. New diagnostic and prognostic biomarkers that are highly specific are urgently needed for its early prognosis. MicroRNAs (miRNAs), a class of non-coding RNAs, are known to control the biological processes involving transcription, post-transcriptional and covalent modifications, splicing, translation, cell differentiation, proliferation, apoptosis, cancer progression, and invasion. Any dysregulation in miRNA expression, demonstrating their oncogenic and tumor-suppressive functions, contributes to cancer progression. MicroRNA-21 (miR-21), an ‘onco-miR’ in breast cancer, is involved in tumor progression and metastasis by suppressing… More >
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