SUYING PU1,#, HUI ZHENG2,#, YUN TAO1, JING SHAO1, MINGNA YANG1, SHUNJUN LI1,*
BIOCELL, Vol.46, No.6, pp. 1545-1555, 2022, DOI:10.32604/biocell.2022.017544
Abstract Intracerebral hemorrhage (ICH) is the most serious type of stroke. High level of thrombin is found in the ICH. Ubiquitin-specific protease (USP) 31, a member of deubiquitinating enzymes family, has been found to negatively regulate the NF-κB pathway. However, the function of USP31 in ICH remains largely unknown. In the present study, the mRNA and protein expression levels of USP31 were measured by real-time PCR and western blot. Flow cytometry was used to measure cell apoptosis and the level of reactive oxygen species (ROS). In the current study, we found the mRNA level of USP31 was decreased in peripheral blood… More >
Login
Register
