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    REVIEW

    Regulation mechanisms of endocrine disruptors on vasodilation and vasoconstriction: Insights from ex vivo models

    MARGARIDA LORIGO1,2, ELISA CAIRRAO1,2,*

    BIOCELL, Vol.46, No.6, pp. 1383-1389, 2022, DOI:10.32604/biocell.2022.018895

    Abstract Cardiovascular diseases (CVD) are one of the leading causes of death worldwide. The knowledge and understanding of CVD are based on the study of vascular physiology and how the smooth muscle cells and tissues perform their different functions. Exposure to endocrine disruptors (EDCs), such as phytoestrogens, polycyclic aromatic hydrocarbons, flame retardants, plasticizers, pesticides, and cosmetics, is an integral and fundamental part of human exposure. Humans are exposed to EDCs by multiple pathways including air, food, water, and consumer products. However, this exposure can lead to several adverse effects on human health, including on the cardiovascular (CV) system. The negative impact… More >

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