ZHIYONG ZHANG1,#, YAN PAN2,#, YAN ZHAO1, MUDAN REN1, YARUI LI1, YUN FENG1, GUIFANG LU1,*, SHUIXIANG HE1,*
BIOCELL, Vol.46, No.8, pp. 1917-1924, 2022, DOI:10.32604/biocell.2022.018847
Abstract Colorectal cancer (CRC) is a heterogeneous cancer, and many risk factors for colorectal cancer have been
established. For CRC metastasis, tumor cell migration, adhesion as well as invasion are important processes. WiskottAldrich syndrome protein family member 3 (WASF3) is necessary for metastasis of various types of cancers. However,
its role in CRC progression has not been fully elucidated. This study examined the in vitro functional roles of WASF3 in
the CRC and explored the underlying molecular mechanisms. We used siRNA-WASF3 to gene silence WASF3 in colon
cancer cell (HCT116) in vitro. The effects of WASF3 silencing on HCT116 cell apoptosis,… More >
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