PENG WU#, MANLI GAO#, JIANJIAN DONG, CHENCHEN XU, BO LI, XUN WANG, YONGZHU HAN, NAN CHENG*
BIOCELL, Vol.45, No.1, pp. 109-117, 2021, DOI:10.32604/biocell.2021.012048
Abstract Wilson disease (WD), known as hepatolenticular degeneration (HLD), is a treatable autosomal recessive disorder
of copper metabolism. Because copper deposits in the liver first, the liver is not only the original defective organ but also the
most affected organ. The liver injury is also one of the main causes of death throughout the course of the disease. Therefore,
the treatment of liver injury is the main task of WD treatment, which is of great significance to improve the prognosis of
patients. Autophagy is a process that promotes cell survival through degradation, recycling, and absorption in order to
maintain the normal… More >
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