Weishan Gao^1,2, Ye Wang^1,2, Xiaoyin Wang^1,2, Xiaochuan Jing^1,2,*

CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.073850 - 12 January 2026

Abstract In the field of intelligent surveillance, weakly supervised video anomaly detection (WSVAD) has garnered widespread attention as a key technology that identifies anomalous events using only video-level labels. Although multiple instance learning (MIL) has dominated the WSVAD for a long time, its reliance solely on video-level labels without semantic grounding hinders a fine-grained understanding of visually similar yet semantically distinct events. In addition, insufficient temporal modeling obscures causal relationships between events, making anomaly decisions reactive rather than reasoning-based. To overcome the limitations above, this paper proposes an adaptive knowledge-based guidance method that integrates external structured… More >

Manaliben Amin^*

Journal on Artificial Intelligence, Vol.8, pp. 1-18, 2026, DOI:10.32604/jai.2026.073895 - 07 January 2026

Abstract Artificial intelligence (AI) is steadily making its way into pharmaceutical validation, where it promises faster documentation, smarter testing strategies, and better handling of deviations. These gains are attractive, but in a regulated environment speed is never enough. Regulators want assurance that every system is reliable, that decisions are explainable, and that human accountability remains central. This paper sets out a Human-in-the-Loop (HITL) AI approach for Computer System Validation (CSV) and Computer Software Assurance (CSA). It relies on explainable AI (XAI) tools but keeps structured human review in place, so automation can be used without creating… More >

Amjad Rehman^1,*, Tanzila Saba¹, Mona M. Jamjoom², Shaha Al-Otaibi³, Muhammad I. Khan¹

CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-15, 2026, DOI:10.32604/cmc.2025.068958 - 10 November 2025

Abstract Modern intrusion detection systems (MIDS) face persistent challenges in coping with the rapid evolution of cyber threats, high-volume network traffic, and imbalanced datasets. Traditional models often lack the robustness and explainability required to detect novel and sophisticated attacks effectively. This study introduces an advanced, explainable machine learning framework for multi-class IDS using the KDD99 and IDS datasets, which reflects real-world network behavior through a blend of normal and diverse attack classes. The methodology begins with sophisticated data preprocessing, incorporating both RobustScaler and QuantileTransformer to address outliers and skewed feature distributions, ensuring standardized and model-ready inputs.… More >

Khulud Salem Alshudukhi^1,*, Sijjad Ali², Mamoona Humayun^3,*, Omar Alruwaili⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 3029-3085, 2025, DOI:10.32604/cmes.2025.073705 - 23 December 2025

Abstract Problem: The integration of Artificial Intelligence (AI) into cybersecurity, while enhancing threat detection, is hampered by the “black box” nature of complex models, eroding trust, accountability, and regulatory compliance. Explainable AI (XAI) aims to resolve this opacity but introduces a critical new vulnerability: the adversarial exploitation of model explanations themselves. Gap: Current research lacks a comprehensive synthesis of this dual role of XAI in cybersecurity—as both a tool for transparency and a potential attack vector. There is a pressing need to systematically analyze the trade-offs between interpretability and security, evaluate defense mechanisms, and outline a… More >

Asma Batool¹, Fahad Ahmed¹, Naila Sammar Naz¹, Ayman Altameem², Ateeq Ur Rehman^3,4, Khan Muhammad Adnan^5,*, Ahmad Almogren^6,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4129-4152, 2025, DOI:10.32604/cmes.2025.073149 - 23 December 2025

Abstract Early and accurate cancer diagnosis through medical imaging is crucial for guiding treatment and enhancing patient survival. However, many state-of-the-art deep learning (DL) methods remain opaque and lack clinical interpretability. This paper presents an explainable artificial intelligence (XAI) framework that combines a fine-tuned Visual Geometry Group 16-layer network (VGG16) convolutional neural network with layer-wise relevance propagation (LRP) to deliver high-performance classification and transparent decision support. This approach is evaluated on the publicly available Kaggle kidney cancer imaging dataset, which comprises labeled cancerous and non-cancerous kidney scans. The proposed model achieved 98.75% overall accuracy, with precision, More >

Mubashir Ali^1,2, Jingzhen Li¹, Zedong Nie^1,*

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 4153-4177, 2025, DOI:10.32604/cmes.2025.073048 - 23 December 2025

Abstract Diabetes imposes a substantial burden on global healthcare systems. Worldwide, nearly half of individuals with diabetes remain undiagnosed, while conventional diagnostic techniques are often invasive, painful, and expensive. In this study, we propose a noninvasive approach for diabetes detection using photoplethysmography (PPG), which is widely integrated into modern wearable devices. First, we derived velocity plethysmography (VPG) and acceleration plethysmography (APG) signals from PPG to construct multi-channel waveform representations. Second, we introduced a novel multiset spatiotemporal feature fusion framework that integrates hand-crafted temporal, statistical, and nonlinear features with recursive feature elimination and deep feature extraction using… More >

Deema Alzamil^1,2,*, Bader Alkhamees², Mohammad Mehedi Hassan^2,3

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.3, pp. 2971-3027, 2025, DOI:10.32604/cmes.2025.070867 - 23 December 2025

Abstract Breast cancer diagnosis relies heavily on many kinds of information from diverse sources—like mammogram images, ultrasound scans, patient records, and genetic tests—but most AI tools look at only one of these at a time, which limits their ability to produce accurate and comprehensive decisions. In recent years, multimodal learning has emerged, enabling the integration of heterogeneous data to improve performance and diagnostic accuracy. However, doctors cannot always see how or why these AI tools make their choices, which is a significant bottleneck in their reliability, along with adoption in clinical settings. Hence, people are adding… More >

Farhad Mortezapour Shiri^*, Thinagaran Perumal, Norwati Mustapha, Raihani Mohamed

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 1389-1485, 2025, DOI:10.32604/cmes.2025.071858 - 26 November 2025

Abstract Human Activity Recognition (HAR) represents a rapidly advancing research domain, propelled by continuous developments in sensor technologies and the Internet of Things (IoT). Deep learning has become the dominant paradigm in sensor-based HAR systems, offering significant advantages over traditional machine learning methods by eliminating manual feature extraction, enhancing recognition accuracy for complex activities, and enabling the exploitation of unlabeled data through generative models. This paper provides a comprehensive review of recent advancements and emerging trends in deep learning models developed for sensor-based human activity recognition (HAR) systems. We begin with an overview of fundamental HAR… More > Graphic Abstract

Tamara Zhukabayeva^1,2, Zulfiqar Ahmad^1,3,*, Nurbolat Tasbolatuly⁴, Makpal Zhartybayeva¹, Yerik Mardenov^1,4, Nurdaulet Karabayev^1,*, Dilaram Baumuratova^1,4

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2573-2599, 2025, DOI:10.32604/cmes.2025.070426 - 26 November 2025

Abstract The Industrial Internet of Things (IIoT), combined with the Cyber-Physical Systems (CPS), is transforming industrial automation but also poses great cybersecurity threats because of the complexity and connectivity of the systems. There is a lack of explainability, challenges with imbalanced attack classes, and limited consideration of practical edge–cloud deployment strategies in prior works. In the proposed study, we suggest an Impact-Aware Taxonomy-Driven Machine Learning Framework with Edge Deployment and SHapley Additive exPlanations (SHAP)-based Explainable AI (XAI) to attack detection and classification in IIoT-CPS settings. It includes not only unsupervised clustering (K-Means and DBSCAN) to extract… More >

Nouman Ahmad^*, Changsheng Zhang

CMC-Computers, Materials & Continua, Vol.85, No.2, pp. 3321-3334, 2025, DOI:10.32604/cmc.2025.067044 - 23 September 2025

Abstract Source code vulnerabilities present significant security threats, necessitating effective detection techniques. Rigid rule-sets and pattern matching are the foundation of traditional static analysis tools, which drown developers in false positives and miss context-sensitive vulnerabilities. Large Language Models (LLMs) like BERT, in particular, are examples of artificial intelligence (AI) that exhibit promise but frequently lack transparency. In order to overcome the issues with model interpretability, this work suggests a BERT-based LLM strategy for vulnerability detection that incorporates Explainable AI (XAI) methods like SHAP and attention heatmaps. Furthermore, to ensure auditable and comprehensible choices, we present a… More >