Masashi Nishida, Shingo Kubo, Yuma Morishita, Kosuke Nishikawa, Kazuyuki Ikeda, Toshiyuki Itoi, Hajime Hosoi
Congenital Heart Disease, Vol.14, No.6, pp. 1087-1093, 2019, DOI:10.1111/chd.12853
Abstract Objective: This study aims to investigate the changes in renal function and levels of
urinary biomarkers before and after cardiac angiography in children with congenital
heart disease (CHD).
Setting: Children with CHD are at a risk for kidney injury during contrast exposure in
cardiac angiography.
Outcome Measures: We measured urinary protein, albumin, N‐acetyl‐β‐D‐glucosaminidase (NAG), β2‐microglobulin (BMG), and liver‐type fatty acid‐binding protein
(L‐FABP) levels, as well as serum creatinine and cystatin C levels, before and after
cardiac angiography in 33 children with CHD.
Results: No significant decrease was noted in either the creatinine‐based or cystatin
C‐based estimated glomerular filtration rate at… More >
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