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    REVIEW

    Efficacy of dexmedetomidine in prevention of junctional ectopic tachycardia and acute kidney injury after pediatric cardiac surgery: A meta‐analysis

    Xin Li MMed*, Chengxin Zhang*, Di Dai MMed, Haiyuan Liu, Shenglin Ge

    Congenital Heart Disease, Vol.13, No.5, pp. 799-807, 2018, DOI:10.1111/chd.12674

    Abstract Objective: We conducted a meta‐analysis to evaluate the effects of prophylactic perioperative dexmedetomidine administration on postoperative junctional ectopic tachycardia (JET) and acute kidney injury (AKI) in pediatric patients having under‐ gone cardiac surgery.
    Design: This systematic review was registered with PROSPERO (CRD42017083880). Databases including PubMed, Cochrane Central Register of Controlled Trials, and Web of Science were searched for randomized controlled trials (RCTs) and observa‐ tional cohort studies from its inception to March 2018. Two reviewers independently screened literature, extracted data, and assessed the quality of included studies using the Jadad scale and Newcastle‐Ottawa score. Meta‐analysis was then conducted by RevMan… More >

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