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    ARTICLE

    Effect of age on the myosin-V immunoreactive myenteric neurons of rats ileum

    JOÃO PAULO FERREIRA SCHOFFEN, MARIA RAQUEL MARÇAL NATALI

    BIOCELL, Vol.31, No.1, pp. 33-39, 2007, DOI:10.32604/biocell.2007.31.033

    Abstract Alterations in the gastrointestinal neuromuscular function related to age have been demonstrated in human and animal models. This study analyzes the effects of the aging process on the area of the neuronal cell bodies of the myenteric plexus in the antimesenteric and intermediate regions of the ileal circumference of Wistar, 12 month-old in comparison 3 month-old animals. The ileum was removed and wholemount preparations immunostained by the antibody anti-myosin-V were processed. The morphometric analyses were performed using a computerized image analysis system, with a subsequent distribution of neurons by size in intervals of 100 μm2. The cellular body morphometry revealed… More >

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