Doris P. Yimgang1, John D. Sorkin2, Charles F. Evans3, Danielle S. Abraham1, Geoffrey L. Rosenthal1,4
Congenital Heart Disease, Vol.13, No.4, pp. 533-540, 2018, DOI:10.1111/chd.12622
Abstract Introduction: Angiotensin converting enzyme inhibitors are commonly prescribed medications
after the Norwood procedure. There are little data that can be used to determine if angiotensin
converting enzyme inhibitors improve interstage outcomes in children with single ventricle defects.
The objective of this study was to investigate the relationship between angiotensin converting
enzyme inhibitors and interstage failure among infants born with hypoplastic left heart syndrome.
Methods: We conducted a retrospective cohort study using data from the National Pediatric Cardiology Quality Improvement Collaborative database (collected between 2008 and 2015). We
used logistic regression models to assess the exposure-outcome associations and… More >