Hayatu Uma^1,*, Abdulaziz Aminu¹, Raghu Cherukupalli², Femi Akindotun Akintomide¹, Abdul Habu³, Aisha Aminu Lawal¹, Adamu Mohammad¹

Congenital Heart Disease, Vol.19, No.6, pp. 635-645, 2024, DOI:10.32604/chd.2025.056641 - 27 January 2025

Abstract Laubry-Pezzi syndrome (L-PS) is a rare congenital heart disease characterized by a ventricular septal defect (VSD) and aortic valve prolapse. These cardiac lesions predispose individuals to infective endocarditis (IE), a life-threatening complication, especially in resource-constrained settings. A 17-year-old male presented with a three-week history of fever and headache, and a one-week history of abdominal pain, vomiting, and diarrhea. On presentation, he appeared toxic, was febrile, tachypneic, tachycardic, and blood pressure of 120/30 mmHg, and heart sounds were S1, S2. Abdominal examination revealed generalized tenderness. A provisional diagnosis of typhoid sepsis with intestinal perforation was considered.… More >

Supaporn Roymanee^1,*, Nantawan Su-angka^1,2, Worakan Promphan^2,3,*, Kanjarut Wongwaitaweewong¹, Jirayut Jarutach¹, Rujira Buntharikpornpun¹, Pimpak Prachasilchai^2,3

Congenital Heart Disease, Vol.18, No.2, pp. 169-181, 2023, DOI:10.32604/chd.2023.021238 - 15 March 2023

Abstract Background: Ventricular septal defect (VSD) is the most common congenital heart disease. Transcatheter VSD closure is an effective treatment for patients with muscular and perimembranous VSD. However, there is a limit data for outlet VSD, especially impact to the aortic valve leaflet after transcatheter closure. This study aims to assess the outcomes of transcatheter closure of the outlet-type ventricular septal defect (OVSD) after 1 postoperative year. Methods: A retrospective study was performed including 50 patients who underwent transcatheter (n = 25) and surgical (n = 25) OVSD closure during the exact time frame at two medical centres. Results: The median age… More > Graphic Abstract

Wenqian Zhang^1,2,#, Chaojie Wang^1,3,#, Lingmei Zhou^2,4,#, Junjie Li², Jijun Shi², Yumei Xie², Mingyang Qian², Shushui Wang², Zhiwei Zhang^1,2,*

Congenital Heart Disease, Vol.16, No.5, pp. 519-528, 2021, DOI:10.32604/CHD.2021.015527 - 03 June 2021

Abstract Objective: This study aims to evaluate the morphology and function of the aortic valve after transcatheter closure of ventricular septal defect (VSD) with aortic valve prolapse (AVP) abased on clinical and radiological outcomes. Methods: From January 2013 to November 2014, 164 consecutive patients (97 males, 59.1%) with VSD and AVP were treated by transcatheter closure. The patients were divided into the mild AVP group (n = 63), moderate AVP group (n = 89) and severe AVP group (n = 12). The clinical and radiological outcomes of these patients were analyzed retrospectively. Results: In total, 146 (89.0%) patients… More >