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    ARTICLE

    Inflation of An Artery Leading to Aneurysm Formation and Rupture

    J. S. Ren*

    Molecular & Cellular Biomechanics, Vol.4, No.1, pp. 55-66, 2007, DOI:10.3970/mcb.2007.004.055

    Abstract Formation and rupture of aneurysms due to the inflation of an artery with collagen fibers distributed in two preferred directions, subjected to internal pressure and axial stretch are examined within the framework of nonlinear elasticity. A two layer tube model with a fiber-reinforced composite based incompressible anisotropic hyperelastic constitutive material is employed to model the stress-strain behavior of the artery wall with distributed collagen fibers. The artery wall takes up a uniform inflation deformation, and there are no aneurysms in the artery under the normal condition. But an aneurysm may be formed in arteries when the stiffness of the fibers… More >

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