Zhuoxi Feng#,1, Jinyang Liu#,2, Zihao Wu1, Ziran Geng1, Zhimin Liu1,*
Congenital Heart Disease, Vol.20, No.5, pp. 625-636, 2025, DOI:10.32604/chd.2025.069214
- 30 November 2025
Abstract Congenitally corrected transposition of the great arteries (CCTGA) is a rare congenital heart disease characterized by atrioventricular, ventriculoarterial, and conduction system discordance, commonly accompanied by atrioventricular block (AVB). Pacing in patients with CCTGA and AVB (both pediatric and adult) poses challenges in strategy selection, procedural complexity, and clinical decision-making due to limited evidence. Conventional morphological left ventricular pacing is widely adopted but may induce ventricular dyssynchrony, heart failure, and tricuspid valve dysfunction. While cardiac resynchronization therapy serves as an upgrade for pacing-induced cardiomyopathy and heart failure, its application may be limited by coronary sinus anatomical… More >