Yuan-Nong Ye1,2,3,*, Ding-Fa Liang2, Abraham Alemayehu Labena4, Zhu Zeng2,*
Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 2731-2741, 2023, DOI:10.32604/iasc.2023.026761
Abstract Essential ncRNA is a type of ncRNA which is indispensable for the survival of organisms. Although essential ncRNAs cannot encode proteins, they are as important as essential coding genes in biology. They have got wide variety of applications such as antimicrobial target discovery, minimal genome construction and evolution analysis. At present, the number of species required for the determination of essential ncRNAs in the whole genome scale is still very few due to the traditional methods are time-consuming, laborious and costly. In addition, traditional experimental methods are limited by the organisms as less than 1% of bacteria can be cultured… More >
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