Shankar Baskar, Andrew N. Redington, Philip R. Khoury, Timothy K. Knilans, David S. Spar, Richard J. Czosek
Congenital Heart Disease, Vol.14, No.2, pp. 201-206, 2019, DOI:10.1111/chd.12684
Abstract Background: Traditional indices to evaluate biventricular (BiV) pacing are load dependent, fail to
assess dynamic changes, and may not be appropriate in patients with congenital heart disease
(CHD). We therefore measured the force‐frequency relationship (FFR) using tissue Doppler‐de‐
rived isovolumic acceleration (IVA) to assess the dynamic adaption of the myocardium and its vari‐
ability with different ventricular pacing strategies.
Methods: This was a prospective pilot study of pediatric and young adult CHD patients with
biventricular or multisite pacing systems. Color‐coded myocardial velocities were recorded at
the base of the systemic ventricular free wall. IVA was calculated at resting heart rate… More >
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