Sharaf J. Malebary^*

CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1301-1317, 2024, DOI:10.32604/cmc.2024.047917

Abstract Brain tumors are a pressing public health concern, characterized by their high mortality and morbidity rates. Nevertheless, the manual segmentation of brain tumors remains a laborious and error-prone task, necessitating the development of more precise and efficient methodologies. To address this formidable challenge, we propose an advanced approach for segmenting brain tumor Magnetic Resonance Imaging (MRI) images that harnesses the formidable capabilities of deep learning and convolutional neural networks (CNNs). While CNN-based methods have displayed promise in the realm of brain tumor segmentation, the intricate nature of these tumors, marked by irregular shapes, varying sizes, uneven distribution, and limited available… More >

KARAN WADHWA¹, PAYAL CHAUHAN¹, SHOBHIT KUMAR², RAKESH PAHWA^3,*, RAVINDER VERMA⁴, RAJAT GOYAL⁵, GOVIND SINGH¹, ARCHANA SHARMA⁶, NEHA RAO³, DEEPAK KAUSHIK^1,*

Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

M. Adimoolam¹, K. Maithili², N. M. Balamurugan³, R. Rajkumar⁴, S. Leelavathy⁵, Raju Kannadasan⁶, Mohd Anul Haq^7,*, Ilyas Khan⁸, ElSayed M. Tag El Din⁹, Arfat Ahmad Khan¹⁰

Intelligent Automation & Soft Computing, Vol.39, No.1, pp. 33-55, 2024, DOI:10.32604/iasc.2024.039009

Abstract At present, the prediction of brain tumors is performed using Machine Learning (ML) and Deep Learning (DL) algorithms. Although various ML and DL algorithms are adapted to predict brain tumors to some range, some concerns still need enhancement, particularly accuracy, sensitivity, false positive and false negative, to improve the brain tumor prediction system symmetrically. Therefore, this work proposed an Extended Deep Learning Algorithm (EDLA) to measure performance parameters such as accuracy, sensitivity, and false positive and false negative rates. In addition, these iterated measures were analyzed by comparing the EDLA method with the Convolutional Neural Network (CNN) way further using… More >

Juhong Tie, Hui Peng^*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 741-757, 2024, DOI:10.32604/cmes.2023.043353

Abstract Accurate automatic segmentation of gliomas in various sub-regions, including peritumoral edema, necrotic core, and enhancing and non-enhancing tumor core from 3D multimodal MRI images, is challenging because of its highly heterogeneous appearance and shape. Deep convolution neural networks (CNNs) have recently improved glioma segmentation performance. However, extensive down-sampling such as pooling or stridden convolution in CNNs significantly decreases the initial image resolution, resulting in the loss of accurate spatial and object parts information, especially information on the small sub-region tumors, affecting segmentation performance. Hence, this paper proposes a novel multi-level parallel network comprising three different level parallel sub-networks to fully… More >

S. Kannan^1,*, S. Anusuya²

CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3835-3851, 2023, DOI:10.32604/cmc.2023.042465

Abstract Gliomas, the most prevalent primary brain tumors, require accurate segmentation for diagnosis and risk assessment. In this paper, we develop a novel deep learning-based method, the Dynamic Hierarchical Attention for Improved Segmentation and Survival Prognosis (DHA-ISSP) model. The DHA-ISSP model combines a three-band 3D convolutional neural network (CNN) U-Net architecture with dynamic hierarchical attention mechanisms, enabling precise tumor segmentation and survival prediction. The DHA-ISSP model captures fine-grained details and contextual information by leveraging attention mechanisms at multiple levels, enhancing segmentation accuracy. By achieving remarkable results, our approach surpasses 369 competing teams in the 2020 Multimodal Brain Tumor Segmentation Challenge. With… More >

Mudassir Khalil¹, Muhammad Imran Sharif^2,*, Ahmed Naeem³, Muhammad Umar Chaudhry¹, Hafiz Tayyab Rauf^4,*, Adham E. Ragab⁵

CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 2031-2047, 2023, DOI:10.32604/cmc.2023.043687

Abstract Early detection of brain tumors is critical for effective treatment planning. Identifying tumors in their nascent stages can significantly enhance the chances of patient survival. While there are various types of brain tumors, each with unique characteristics and treatment protocols, tumors are often minuscule during their initial stages, making manual diagnosis challenging, time-consuming, and potentially ambiguous. Current techniques predominantly used in hospitals involve manual detection via MRI scans, which can be costly, error-prone, and time-intensive. An automated system for detecting brain tumors could be pivotal in identifying the disease in its earliest phases. This research applies several data augmentation techniques… More >

Mohammed Aly^1,*, Abdullah Shawan Alotaibi²

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 557-582, 2023, DOI:10.32604/cmc.2023.042493

Abstract Tumor segmentation is a valuable tool for gaining insights into tumors and improving treatment outcomes. Manual segmentation is crucial but time-consuming. Deep learning methods have emerged as key players in automating brain tumor segmentation. In this paper, we propose an efficient modified U-Net architecture, called EMU-Net, which is applied to the BraTS 2020 dataset. Our approach is organized into two distinct phases: classification and segmentation. In this study, our proposed approach encompasses the utilization of the gray-level co-occurrence matrix (GLCM) as the feature extraction algorithm, convolutional neural networks (CNNs) as the classification algorithm, and the chi-square method for feature selection.… More >

Tawfeeq Shawly¹, Ahmed Alsheikhy^2,*

CMC-Computers, Materials & Continua, Vol.77, No.1, pp. 425-443, 2023, DOI:10.32604/cmc.2023.040561

Abstract According to the World Health Organization (WHO), Brain Tumors (BrT) have a high rate of mortality across the world. The mortality rate, however, decreases with early diagnosis. Brain images, Computed Tomography (CT) scans, Magnetic Resonance Imaging scans (MRIs), segmentation, analysis, and evaluation make up the critical tools and steps used to diagnose brain cancer in its early stages. For physicians, diagnosis can be challenging and time-consuming, especially for those with little expertise. As technology advances, Artificial Intelligence (AI) has been used in various domains as a diagnostic tool and offers promising outcomes. Deep-learning techniques are especially useful and have achieved… More >

Xiaoliang Lei¹, Xiaosheng Yu^2,*, Hao Wu³, Chengdong Wu^2,*, Jingsi Zhang²

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3797-3811, 2023, DOI:10.32604/cmc.2023.042069

Abstract Accurate tumor segmentation from brain tissues in Magnetic Resonance Imaging (MRI) imaging is crucial in the pre-surgical planning of brain tumor malignancy. MRI images’ heterogeneous intensity and fuzzy boundaries make brain tumor segmentation challenging. Furthermore, recent studies have yet to fully employ MRI sequences’ considerable and supplementary information, which offers critical a priori knowledge. This paper proposes a clinical knowledge-based hybrid Swin Transformer multimodal brain tumor segmentation algorithm based on how experts identify malignancies from MRI images. During the encoder phase, a dual backbone network with a Swin Transformer backbone to capture long dependencies from 3D MR images and a… More >

Muhammad Attique Khan^1,2, Reham R. Mostafa³, Yu-Dong Zhang², Jamel Baili⁴, Majed Alhaisoni⁵, Usman Tariq⁶, Junaid Ali Khan¹, Ye Jin Kim⁷, Jaehyuk Cha^7,*

CMC-Computers, Materials & Continua, Vol.76, No.3, pp. 3029-3047, 2023, DOI:10.32604/cmc.2023.038838

Abstract Manual diagnosis of brain tumors using magnetic resonance images (MRI) is a hectic process and time-consuming. Also, it always requires an expert person for the diagnosis. Therefore, many computer-controlled methods for diagnosing and classifying brain tumors have been introduced in the literature. This paper proposes a novel multimodal brain tumor classification framework based on two-way deep learning feature extraction and a hybrid feature optimization algorithm. NasNet-Mobile, a pre-trained deep learning model, has been fine-tuned and two-way trained on original and enhanced MRI images. The haze-convolutional neural network (haze-CNN) approach is developed and employed on the original images for contrast enhancement.… More >