Mingjie Zhang¹, Wenyi Luo¹, Liping Wang¹, Xi Chen¹, Nan Bao^2,*, Zhuoming Xu^1,*

Congenital Heart Disease, Vol.15, No.5, pp. 377-386, 2020, DOI:10.32604/CHD.2020.011983

Abstract Background: This retrospective cohort study aimed to explore the causes of death in children with congenital heart disease (CHD) after cardiac surgery in one of the biggest cardiac centers for children with CHD in China. Methods: A total of 26,856 children undergoing cardiac surgery from January 1, 2012 to December 31, 2019 were included. Based on the clinical data, the causes of death were divided into ten categories and further compared among different periods, types of CHD and surgical procedures. Results: Of all patients, 513 (1.9%) died (median age 162 d, median weight 5.6 kg). The mortality in 2016–2019 was… More >

Shengwen Guo, Yuanyuan Tong, Liting Bai, Peiyao Zhang, Xin Duan^*, Jinping Liu^*

Congenital Heart Disease, Vol.15, No.5, pp. 275-285, 2020, DOI:10.32604/CHD.2020.011894

Abstract Objective: Serum ferritin has been identified as a prognostic marker in patients with a variety of diseases. In the present study we aim to determine the prevalence of risk factors and outcomes for hyperferritinemia in children undergoing cardiac surgery with cardiopulmonary bypass for congenital heart defects. Methods: The serum ferritin levels of 457 children between the ages of twentyeight days and three years undergoing cardiopulmonary bypass surgery between June 1, 2017 and June 1, 2018 were analyzed. The prevalence of early postoperative hyperferritinemia was investigated; hyperferritinemia was defined as a ferritin level ≥250 ng/ml. Multivariable regression models including candidate risk… More >

Or Bercovich¹, Tal Tirosh-Wagner², Lior Goldberg¹, Amir Vardi³, David Mishali⁴, Gideon Paret^1,#, Yael Nevo-Caspi^1,*,#

Congenital Heart Disease, Vol.15, No.4, pp. 239-249, 2020, DOI:10.32604/CHD.2020.011576

Abstract Objective: To test the hypothesis that circulating miRNAs-146a, -146b, -155, and -21 reflect the inflammatory state of children following heart surgery, and that they may, therefore, correlate with postoperative parameters. We aimed to quantify miRNAs in blood samples from pediatric patients before and 6, 12, and 24 hours after surgery and to evaluate correlations between the miRNA levels and the postoperative course. Setting: PICU. Patients: Forty-two pediatric patients with CHD who underwent cardiac surgery at Safra Children’s Hospital between 2012–2016. Interventions: none. Outcome Measures: The primary outcomes were the postoperative cardiac complications and the secondary outcomes were the length of… More >

Alvise Guariento^1,2, Ilias P. Doulamis³, David Blitzer⁴, Claudia Cattapan², Massimo A. Padalino², Vladimiro L. Vida^2,*

Congenital Heart Disease, Vol.15, No.3, pp. 127-139, 2020, DOI:10.32604/CHD.2020.012197

Abstract Background: In an effort to reduce postoperative trauma and achieve more cosmetic results, minimally invasive approaches to correct congenital heart anomalies have been recently proposed and increasingly adopted. Here we describe our experience for the past 23 years. Methods: Patients who underwent a surgical procedure between February 1996 and March 2019 with a minimally invasive approach for the correction of congenital heart disease in our center were included in this study. A statistical analysis was carried out to compare the results of the different minimally invasive techniques. A meta-analysis was conducted to compare our results in patients undergoing atrial septal… More >

Michela Palma, Giancarlo Scognamiglio^*, Flavia Fusco, Assunta Merola, Anna Correra, Diego Colonna, Emanuele Romeo, Berardo Sarubbi

Congenital Heart Disease, Vol.15, No.1, pp. 33-49, 2020, DOI:10.32604/CHD.2020.011523

Abstract Adults with congenital heart disease (ACHD) constitute a growing population with complex cardiac physiopathology and frequent extra-cardiac involvement. The recent dramatic improvement of their life expectancy has resulted in an increasing proportion of ACHD patients requiring non-cardiac surgery. While a large body of evidence demonstrated the importance of an accurate risk assessment in patients with acquired heart disease before noncardiac surgery in order to reduce perioperative morbidity and mortality and detailed algorithms have been released by international societies, no specific guidelines are available for the perioperative management in this population. Nonetheless, understanding the complex anatomy and unusual physiology of both… More >

Wen-Yi Luo¹, Zhuo-Ming Xu¹, Li Hong², Qian-Yue Wu¹, Yue-Yue Zhang¹

Congenital Heart Disease, Vol.12, No.6, pp. 777-782, 2017, DOI:10.1111/chd.12489

Abstract Background: Food allergy is a rapidly growing public health concern because of its increasing prevalence, as well as life-threatening potential. There is limited knowledge on the nutritional status for the pediatric congenital heart disease (CHD) patients with food allergy.
Objective: This study investigated both clinical and nutritional outcomes according to the CHD infants with food allergy.
Methods: Forty CHD infants with food allergy and 39 controls were recruited in Shanghai, China. The height and weight for age and weight for height were converted to z-scores to evaluate their effects on nutritional status before and after CHD operation.
Results: Cow’s milk… More >

Christopher Snyder

Congenital Heart Disease, Vol.12, No.5, pp. 692-692, 2017, DOI:10.1111/chd.12542

Abstract This article has no abstract. More >

Anoymous

Congenital Heart Disease, Vol.12, No.5, pp. 649-691, 2017, DOI:10.1111/chd.12538

Abstract This article has no abstract. More >

Amir-Reza Hosseinpour¹, Mathieu van Steenberghe¹, Marc-André Bernath², Stefano Di Bernardo³, Marie-Hélène Pérez⁴, David Longchamp⁴, Mirko Dolci², Yann Boegli², Nicole Sekarski³, Javier Orrit¹, Michel Hurni¹, René Prêtre¹, Jacques Cotting⁴

Congenital Heart Disease, Vol.12, No.5, pp. 570-577, 2017, DOI:10.1111/chd.12485

Abstract Objective: An important aspect of perioperative care in pediatric cardiac surgery is maintenance of optimal hemodynamic status using vasoactive/inotropic agents. Conventionally, this has focused on maintenance of cardiac output rather than perfusion pressure. However, this approach has been abandoned in our center in favor of one focusing primarily on perfusion pressure, which is presented here and compared to the conventional approach.
Design: A retrospective study.
Setting: Regional center for congenital heart disease. University Hospital of Lausanne, Switzerland.
Patients: All patients with Aristotle risk score ≥8 that underwent surgery from 1996 to 2012 were included. Patients operated between 1996 and 2005… More >

Jennifer K. Peterson¹, Yanjun Chen², Danh V. Nguyen³, Shaun P. Setty¹

Congenital Heart Disease, Vol.12, No.4, pp. 520-532, 2017, DOI:10.1111/chd.12475

Abstract Objective: Despite overall improvements in congenital heart disease outcomes, racial and ethnic disparities have continued. The purpose of this study is to examine the effect of race and ethnicity, as well as other risk factors on congenital heart surgery length of stay and in-hospital mortality.
Design: From the 2012 Healthcare Cost and Utilization Project Kids Inpatient Database (KID), we identified 13 130 records with Risk Adjustment in Congenital Heart Surgery complexity scoreeligible procedures. Multivariate logistic and linear regression modeling with survey weights, stratification and clustering was used to examine the relationships between predictor variables and length of stay as well… More >