Rachel Wong1, Mohammed Al‐Omary2, David Baker2, Neil Spratt1,2, Andrew Boyle1,2, Natasha Baker Cert1, Peter Howe1, Nicholas Collins2
Congenital Heart Disease, Vol.14, No.4, pp. 638-644, 2019, DOI:10.1111/chd.12763
Abstract Objectives: Improvements in the management of complex congenital heart disease,
including those with single ventricle physiology, have resulted in increased survival.
As this population ages, the recognition of cognitive impairment is increasingly im‐
portant. At present, little is known about the potential mechanisms of cognitive dys‐
function. In this cross‐sectional study, we aimed to characterize the nature of
abnormalities in cerebral blood flow and the relationship to cognitive deficits in
adults with single ventricular physiology.
Patients: Ten adults with single ventricular physiology (age 18‐40 years) and 12 age‐
and gender‐matched controls underwent transcranial Doppler ultrasound and ac‐
companying cognitive assessment.
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