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  • Open Access

    ARTICLE

    Germline Predisposition in Pediatric Central Nervous System Tumors: Insights from a Multigene Panel Study

    Meerim Park1, Seungman Park2, Ensel Oh3, Jongmun Choi4, Mi Mi Kwon1, Seog-Yun Park5, Jun Ah Lee1, Hyeon Jin Park1,*

    Oncology Research, Vol.34, No.6, 2026, DOI:10.32604/or.2026.079120 - 21 May 2026

    Abstract Objectives: Germline variants in cancer predisposition genes have been increasingly recognized in pediatric cancers. However, their spectrum in East Asian children with central nervous system (CNS) tumors remains insufficiently defined. This study investigated the prevalence and clinical significance of pathogenic or likely pathogenic (P/LP) germline mutations in Korean children, adolescents, and young adults (AYAs) with CNS tumors. Methods: We performed targeted next-generation sequencing of 358 cancer-associated genes using peripheral blood DNA from 108 patients. Germline variants were classified according to ACMG/AMP guidelines and curated using ClinVar and relevant literature. Results: Among 108 patients, 17 (15.7%) carried P/LP… More >

  • Open Access

    ARTICLE

    Effects of Parental Cognitive Enhancement Combined with Parent–Child Psychological Support on Symptom Control and Prognosis in Children with Allergic Rhinitis

    Yan Shen1, Lisheng Xie2,*

    International Journal of Mental Health Promotion, Vol.28, No.4, 2026, DOI:10.32604/ijmhp.2026.078186 - 28 April 2026

    Abstract Objectives: Pediatric allergic rhinitis (AR) is a highly prevalent chronic inflammatory airway disease that significantly impairs children’s sleep, learning performance, and quality of life. Despite standardized pharmacotherapy, long-term symptom control remains suboptimal, which is related to the poor treatment compliance of patients and the insufficient disease awareness of parents. This study aimed to evaluate the effects of parental cognitive enhancement combined with parent–child psychological support on symptom control, the quality of life, and underlying intervention mechanisms in children aged 6–14 years with moderate to severe AR. Methods: A total of 150 children aged 6–14 years with… More >

  • Open Access

    ARTICLE

    Analysis of Relevant Factors Associated with Postoperative Recovery after Anomalous Origin of the Left Coronary Artery from Pulmonary Artery Surgery in Children

    Jia Yuan1,2,#, Yanxing Lv2,#, Xinyuan Ding3, Yunyi Zeng1, Li Ma4, Hang Yang1, Lin Jiang1, Kamil Bildebayev5, Boiko Yuliya Nikolaevna5, Na Zhou1,*

    Structural and Congenital Heart Disease, Vol.21, No.1, 2026, DOI:10.32604/schd.2026.076648 - 31 March 2026

    Abstract Backgorund: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly of coronary artery anatomy, usually diagnosed in infancy, but adults may also be affected by this deformity. Objectives: The aim of this study is to examine long-term outcomes in patients with ALCAPA and analyze the relevant factors influencing postoperative outcomes. Methods: The records of patients with ALCAPA admitted from January 2015 to December 2024 were retrospectively reviewed. Clinical data of the patients were retrieved from the records. The follow-up data included mortality rates and complications. Kaplan-Meier survival curves were… More >

  • Open Access

    ARTICLE

    Does the Depression, Anxiety, and Stress Scales–Youth Version (DASS-Y) Remain Consistent Across Time and Diverse School-Aged Youth?

    Xu Wang1,2, Cui-Hong Cao2,3, Xiao-Ling Liao4, Xing-Yong Jiang5, Mark D. Griffiths6, I-Hua Chen7,*, Chung-Ying Lin8,9,*

    International Journal of Mental Health Promotion, Vol.28, No.3, 2026, DOI:10.32604/ijmhp.2026.075149 - 31 March 2026

    Abstract Background: The recently developed Depression, Anxiety, and Stress Scales–Youth Version (DASS-Y) shows promise as a tool for assessing youth mental health, but its consistency across timepoints and diverse ages remains underexplored. The present study evaluated whether the DASS-Y reliably measured depression, anxiety, and stress among school-aged youth (aged 9–18 years) across distinct time periods and educational stages. Methods: Two studies were conducted. Study 1 examined consistency over three months using data from 736 Central Chinese high school students who completed surveys at both timepoints. Study 2 tested consistency across educational levels among 2321 primary and 1676… More >

  • Open Access

    ARTICLE

    Physical Activity or Organized Sport, Which Is Better for Depression? A Perspective on Attributable Healthcare Costs in Chinese Children and Adolescents

    Xiaojiao Sun1,*, Shuge Zhang2,3,*

    International Journal of Mental Health Promotion, Vol.28, No.3, 2026, DOI:10.32604/ijmhp.2026.073845 - 31 March 2026

    Abstract Background: Depression is a growing public health concern among Chinese children and adolescents, with substantial healthcare costs. Physical activity (PA) and organized sport are modifiable behaviours protective against depression. This study, therefore, estimated the healthcare costs of depression attributable to insufficient PA and organized sport participation. Methods: A cost-of-illness approach with population attributable fraction (PAF) was applied. Relative risks were derived from longitudinal evidence, prevalence estimates from national Chinese surveys, and depression case numbers from the Global Burden of Disease 2021. Direct healthcare costs were extrapolated from European Union estimates, adjusted to 2024 US dollars (USD),… More >

  • Open Access

    REVIEW

    Investigating the Mental Health of Left-Behind Children in China’s Rural Areas: A Systematic Review Approach

    Jian Li1,*, Yide Chen2, Xinyi Zhao3, Eryong Xue3,*

    International Journal of Mental Health Promotion, Vol.28, No.3, 2026, DOI:10.32604/ijmhp.2026.073286 - 31 March 2026

    Abstract Background: The mobility of people in rural areas may lead to more and more left-behind children (LBC) appearing, and being an LBC brings a lot of risks to mental health, which could greatly hinder children’s development and undermine their happiness and safety in life. Previous scholars have conducted plenty of studies that focused on Chinese rural LBCs’ mental health issues, such as what they exactly look like and some potential factors, but there remains a paucity of reviews about the relationship among certain mental health issues. We will try to figure out how the most common… More >

  • Open Access

    CASE REPORT

    Clear cell sarcoma of the kidney with inferior vena cava tumor thrombus in a pediatric patient: a case report

    Bo Yin1,#, Xingyu Long2,#, Zhi Wang1, Feng Ning1, Kan Wang2, Jun He1,*

    Canadian Journal of Urology, Vol.33, No.1, pp. 201-210, 2026, DOI:10.32604/cju.2025.067189 - 28 February 2026

    Abstract Background: Clear cell sarcoma of the kidney (CCSK) is a rare and highly aggressive pediatric renal malignancy with a marked propensity for metastatic spread. Cases of CCSK associated with inferior vena cava (IVC) tumor thrombus (IVCTT) are exceptionally uncommon in the literature. We report a case of CCSK with IVCTT in a 15-month-old male infant. Case Description: We reported a case admitted in May 2020 for a 3-day history of fever and hematuria. Abdominal CT revealed an unevenly enhanced mass and low-density shadows within the IVC. The diagnosis of CCSK was confirmed via needle biopsy. The… More >

  • Open Access

    ARTICLE

    Parental involvement and social skills of school-aged children with intellectual disabilities: The role of parenting stress and social support

    Yuting Han, Nana Jiang, Yuan Yuan*

    Journal of Psychology in Africa, Vol.36, No.1, pp. 79-87, 2026, DOI:10.32604/jpa.2026.069939 - 26 February 2026

    Abstract This study investigated the effects of parental involvement, parenting stress, and social support on the social skills of school-aged children (6–18 years old) with intellectual disabilities (ID). Data were collected from 280 Chinese parents (mothers = 70.0%, fathers = 30.0%) of children with ID through purposive sampling and analyzed using partial least squares structural equation modeling (PLS-SEM). The results indicated that parental involvement not only directly enhanced children’s social skills but also indirectly improved them by alleviating parenting stress, which acted as a partial mediator. Contrary to the stress-buffering hypothesis, social support did not moderate More >

  • Open Access

    ARTICLE

    Home Mealtimes in Kenya and Zambia: Recognising culturally grounded practices that foster healthy eating behaviours

    Jeofrey Mtemeri1,*, Hetal Patel1, Rehema Abiyo2, Claire Farrow1, Megan Jarman1, Haatembo Mooya3, Laura Shapiro1, Barnabas Simatende4, Pamela Wadende5, Henriette Zeidler6

    Journal of Psychology in Africa, Vol.36, No.1, pp. 53-63, 2026, DOI:10.32604/jpa.2026.069558 - 26 February 2026

    Abstract Globally, mealtimes provide key insights into cultural and social values and practices. We examine mealtime environments and eating practices in two different African settings using quantitative observational and questionnaire data. Participating families (N = 80) were recruited from two rural locations in Zambia and Kenya. Results following descriptive analysis showed that meals are typically taken as a family in a sociable context, providing opportunities to nurture children’s positive behaviours. In both communities, mothers (71.25%) were most likely to be present and typically prepared meals and provided the food. We observed a few distractions being used… More >

  • Open Access

    ARTICLE

    Mindfulness-Based Stress Reduction for Caregiving Stress in Parents of Children with Leukemia

    Jinpan Wang1,#, Yue Yuan2,#,*

    International Journal of Mental Health Promotion, Vol.28, No.1, 2026, DOI:10.32604/ijmhp.2025.071212 - 28 January 2026

    Abstract Background: Childhood leukemia, a malignant proliferative disorder of the hematopoietic system and the most common childhood cancer, poses a significant threat to the lives and health of affected children. For parents, a leukemia diagnosis in their child is a profoundly traumatic event. As primary caregivers, they endure immense psychological distress and caregiving stress throughout the prolonged and demanding treatment process, which can adversely affect their own well-being and caregiving capacity. However, the psychological mechanisms, such as the role of mindfulness, linking caregiver stress to parental coping strategies remain underexplored, and evidence-based interventions to support these parents… More >

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