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  • Open Access

    ARTICLE

    A Comprehensive Brain MRI and Neurodevelopmental Dataset in Children with Tetralogy of Fallot

    Yang Xu1,#, Yaqi Zhang2,#, Meijiao Zhu3, Pengcheng Xue4, Siyu Ma1, Di Yu1, Liang Hu1, Yuxi Zhang1, Wei Peng1, Jirong Qi1, Xuyun Wen4, Ming Yang3, Xuming Mo1,2,5,*

    Congenital Heart Disease, Vol.20, No.5, pp. 559-570, 2025, DOI:10.32604/chd.2025.072242 - 30 November 2025

    Abstract Background: The life-course management of children with tetralogy of Fallot (TOF) has focused on demonstrating brain structural alterations, developmental trajectories, and cognition-related changes that unfold over time. Methods: We introduce an magnetic resonance imaging (MRI) dataset comprising TOF children who underwent brain MRI scanning and cross-sectional neurocognitive follow-up. The dataset includes brain three-dimensional T1-weighted imaging (3D-T1WI), three-dimensional T2-weighted imaging (3D-T2WI), and neurodevelopmental evaluations using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition (WPPSI-IV). Results: Thirty-one children with TOF (age range: 4–33 months; 18 males) were recruited and completed corrective surgery at the Children’s Hospital of Nanjing More >

  • Open Access

    ARTICLE

    Psychosocial Functioning and Quality of Life of Recipients in Pediatric Heart Transplant

    Min Zeng1, Fan Yang1, Jie Huang2, Zhongkai Liao2, Sheng Liu3, Xu Wang1,*

    Congenital Heart Disease, Vol.20, No.5, pp. 581-589, 2025, DOI:10.32604/chd.2025.070100 - 30 November 2025

    Abstract Background: Psychosocial functioning and quality of life (QoL) are strongly associated with outcomes in pediatric heart transplant recipients. The data in pediatric transplantation, however, is limited. This study aims to investigate the associations of perioperative anxiety and depression with postoperative complications, sociodemographic and clinical characteristics. Methods: This observational, analytical, longitudinal study included 42 pediatric participants aged 8 to 16 years old. Preoperative psychological assessments were completed by 36 children, the remaining 6 were unable to participate due to invasive ventilation, extracorporeal membrane oxygenation (ECMO), and physical debilitation. Postoperatively, all 42 subjects completed the psychosocial evaluations. Data… More >

  • Open Access

    ARTICLE

    Effectiveness of an 8-Week Game-Based Physical Activity Program in Reducing Post-Traumatic Stress among Children Affected by the 2023 Kahramanmaraş Earthquakes

    Burak Canpolat1,*, Göktuğ Norman2, Cemal Gündoğdu2, Şakir Tüfekçi2, Yalın Aygün2, Taylan Akbuğa3

    International Journal of Mental Health Promotion, Vol.27, No.11, pp. 1781-1795, 2025, DOI:10.32604/ijmhp.2025.069852 - 28 November 2025

    Abstract Objectives: This study examines the effectiveness of an eight-week game-based physical activity program designed to reduce post-traumatic stress levels in children affected by the Kahramanmaraş-centered earthquakes that occurred in Turkey on 06 February 2023. Following the earthquake, millions of children experienced significant changes in their education and living conditions, adversely affecting their psychological health. Methods: The therapeutic effects of physical activity on post-traumatic stress disorder (PTSD) are frequently emphasized in the literature, and this study specifically focuses on the impact of game-based exercises. The research employed an experimental design, involving 80 earthquake-affected children aged 10 to… More >

  • Open Access

    ARTICLE

    Outcomes and Toxicity of Adult Medulloblastoma Treated with Pediatric Multimodal Protocols: A Single-Institution Experience

    Antonio Ruggiero1,2,*, Dario Talloa1, Alberto Romano1, Giorgio Attinà1, Stefano Mastrangelo1,2, Palma Maurizi1,2, Tommaso Verdolotti3, Gianpiero Tamburrini4,5, Silvia Chiesa6, Rina di Bonaventura7, Pier Paolo Mattogno7, Alessandro Olivi7,8, Alessio Albanese7,8

    Oncology Research, Vol.33, No.12, pp. 3855-3867, 2025, DOI:10.32604/or.2025.067948 - 27 November 2025

    Abstract Background: Adult medulloblastoma (MB) represents less than 1% of central nervous system malignancies, lacking standardized therapeutic approaches due to its rarity. This retrospective single-center analysis aimed to assess survival outcomes and treatment-associated toxicities in adult MB patients managed with pediatric-derived protocols. Methods: Eighteen patients (≥18 years) with MB treated at Fondazione Policlinico Universitario Agostino Gemelli Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) (January 1997–January 2024) were analyzed. All received craniospinal radiotherapy with posterior fossa boost, followed by adjuvant chemotherapy utilizing pediatric regimens (PNET3, PNET4, PNET5, or high-risk protocols incorporating high-dose chemotherapy with autologous… More >

  • Open Access

    COMMUNICATION

    A prospective randomized trial comparing dusting and fragmentation techniques using Holmium:YAG laser for pediatric ureteral stones

    Ahmed Ahmed1, Bilal Farhan2, Amr Alam-Eldin1, Maged Amin Helmy1, Mohammed Mostafa Hussein1, Zakieldahshoury Mohamed1, Hassaan A. Gad1, Suraj Nayan Vodnala3,*

    Canadian Journal of Urology, Vol.32, No.5, pp. 483-490, 2025, DOI:10.32604/cju.2025.067228 - 30 October 2025

    Abstract Background: As occurrence rates of pediatric ureteral stones have increased, evaluation of optimal treatment modalities has become imperative. This study’s primary goal is to compare outcomes between dusting and fragmentation techniques using Holmium:YAG (Ho:YAG) laser lithotripsy in children with ureteral stones. Methods: A prospective randomized study was conducted at Aswan University Hospitals from June 2023 to December 2024. One hundred children, under the age of 18, with single, mid- or distal, ureteral stones (5–20 mm) were randomized into two groups. Group A received laser dusting (0.2–0.6 J, 20–40 Hz), while Group B received fragmentation (0.8–1.5… More >

  • Open Access

    ARTICLE

    Fathers’ overprotective parenting and young children’s problem behaviors: Mediating by mothers’ overprotective attitudes and parenting stress

    Ruiqian Li1,*, Peibing Zheng1, Mengxin Yan1, Xinyi Zhou2, Ziyu Wu1, Yiting Wang1

    Journal of Psychology in Africa, Vol.35, No.5, pp. 681-688, 2025, DOI:10.32604/jpa.2025.069421 - 24 October 2025

    Abstract This study examined the relationship between paternal overprotective parenting and problem behaviors of preschool children, and maternal overprotective attitudes and parenting stress mediation of that relationship. Data were collected from 265 families, including parents and preschool children (ages 3–6). The results revealed that paternal overprotective attitudes significantly influenced maternal overprotective attitudes and maternal parenting stress. Maternal overprotective attitudes, in turn, increased maternal parenting stress, exacerbated children’s problem behaviors. Paternal overprotective attitudes indirectly contributed to these behaviors through both maternal overprotective attitudes and parenting stress. The effect was more pronounced on boy than girl younger than More >

  • Open Access

    ARTICLE

    Long-Term Follow-Up of Percutaneous Stent Implantation for Residual Pulmonary Artery Stenosis in Pediatric Patients after Surgical Repair of Complicated Congenital Heart Diseases

    Yifan Li1,#, Xu Huang2,#, Bingyu Ma3, Ling Sun1, Shushui Wang1, Zhiwei Zhang1, Yumei Xie1,*

    Congenital Heart Disease, Vol.20, No.4, pp. 463-475, 2025, DOI:10.32604/chd.2025.068286 - 18 September 2025

    Abstract Objective: The aim of the present study was to investigate long-term efficacy and safety of percutaneous stent implantation for residual pulmonary artery stenosis (PAS) in pediatric patients after surgical repair of complicated congenital heart diseases (CHDs). Methods: All pediatric patients diagnosed with residual PAS after surgical repair of complicated CHDs between 1996 and 2020 were retrospectively enrolled in the study. Results: A total of 41 patients (30 males, 11 females; median age 5.0 years, median weight 17 kg) were followed-up for a median of 7.1 years. Follow-up echocardiography results demonstrated that the target vessel diameter increased from… More >

  • Open Access

    COMMENTARY

    Asymptomatic Ebstein’s Anomaly in Children and Adults: Intervene or Observe?

    Runzhang Liang1,2, Haiyun Yuan1,2, Shusheng Wen1,2,*

    Congenital Heart Disease, Vol.20, No.4, pp. 447-449, 2025, DOI:10.32604/chd.2025.067838 - 18 September 2025

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Negotiable Fate Belief and Suicidal Ideation among Left-Behind Children: The Mediating Role of Coping Self-Efficacy and Gender Differences

    Xiao Hu1,#, Biao Li2,#, Jun Qin2,*

    International Journal of Mental Health Promotion, Vol.27, No.8, pp. 1203-1220, 2025, DOI:10.32604/ijmhp.2025.066297 - 29 August 2025

    Abstract Objectives: Suicidal ideation is a strong predictor of suicide deaths, which refers to the consideration or desire to give up one’s own life. Left-behind children in rural China are more vulnerable to psychological problems and suicidal ideation compared to their non-left-behind peers. The aim of the current study was to examine two potential protective factors, negotiable fate belief and coping self-efficacy, and to test the mediating role of coping self-efficacy in the relationship between negotiable fate belief and suicidal ideation. We also analyzed gender differences in this mediation model. Methods: A cross-sectional survey was conducted… More >

  • Open Access

    ARTICLE

    Monetary reward and punishment effects on behavioral inhibition in children with attention deficit hyperactivity disorder tendencies

    Huifang Yang1,*, Peixuan Kuang2

    Journal of Psychology in Africa, Vol.35, No.4, pp. 535-540, 2025, DOI:10.32604/jpa.2025.070124 - 17 August 2025

    Abstract The study investigated the effects of monetary rewards and punishments on the behavioral inhibition in children with attention deficit hyperactivity disorder (ADHD) tendencies. The present study adopted the signal stopping task paradigm, with 66 children with ADHD tendencies as the research subjects. A mixed design of 2 (reward and punishment type: reward, punishment) × 2 (stimulus type: monetary stimulus, social stimulus) was used. The analysis applied a between intervention group (with reward and punishment type variables) and within type of reward approach (by stimulus type as intra subject variables). The results showed that monetary punishment More >

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