Christine M. Riley1, Christopher W. Mastropietro2, Peter Sassalos3, Jason R. Buckley4, John M. Costello4, Ilias Iliopoulos5, Aimee Jennings6, Katherine Cashen7, Sukumar Suguna Narasimhulu8, Keshava M. N. Gowda9, Arthur J. Smerling10, Michael Wilhelm11, Aditya Badheka12, Adnan Bakar13,14, Elizabeth A. S. Moser15, Venu Amula16
Congenital Heart Disease, Vol.14, No.6, pp. 1078-1086, 2019, DOI:10.1111/chd.12849
Abstract Background: Elevated pulmonary vascular resistance (PVR) is common following
repair of truncus arteriosus. Inhaled nitric oxide (iNO) is an effective yet costly
therapy that is frequently implemented postoperatively to manage elevated PVR.
Objectives: We aimed to describe practice patterns of iNO use in a multicenter
cohort of patients who underwent repair of truncus arteriosus, a lesion in which
recovery is often complicated by elevated PVR. We also sought to identify patient
and center factors that were more commonly associated with the use of iNO in the
postoperative period.
Design: Retrospective cohort study.
Setting: 15 tertiary care pediatric referral centers.
Patients:… More >