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  • Open Access


    Gastric Cancer with Bone Marrow Invasion and Disseminated Intravascular Coagulation: A Case Report

    Lilan Chen, Lu Lu, Xinlei Gong, Yichen Xu, Xiaoyuan Chu*, Guichun Huang*

    Oncologie, Vol.24, No.3, pp. 599-604, 2022, DOI:10.32604/oncologie.2022.023310

    Abstract Gastric cancer is the fifth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide in 2020. Gastric cancer usually undergoes lymph node metastasis and implantation metastasis, but bone metastasis and bone marrow invasion are rare. However, gastric cancer patients with bone marrow invasion usually have cancer emergency, so special attention should be paid in clinical practice. Herein, we analyzed the clinical characteristics of an asian gastric cancer patient with bone marrow invasion and disseminated intravascular coagulation (DIC) in our hospital and summarized the diagnosis and treatment experience to provide a reference More >

  • Open Access


    A 20-Year Follow-up after the Fontan Operation in a Population with Hypoplastic Left Heart Syndrome

    Eleni P. Asimacopoulos*, Steven J. Staffa, Peter C. Laussen, Kirsten C. Odegard

    Congenital Heart Disease, Vol.17, No.5, pp. 579-590, 2022, DOI:10.32604/chd.2022.020334

    Abstract Background: Thromboembolic events are a cause of significant morbidity and mortality in the Fontan population. We previously reported on coagulation profile changes in a cohort of patients with hypoplastic left heart syndrome (HLHS) from Stage I through Fontan completion. In this report, we examine their clinical status, anticoagulation and incidence of thromboembolic events up to 20 years post Fontan. Methods: A retrospective chart review was conducted for twenty (20) surviving patients, from 1998 through December 2020. Patients who underwent orthotopic heart transplantation (OTx) were followed until their transplant. Patients who were found in the original study… More >

  • Open Access


    Experimental Study on the Treatment of Tertiary Oil Recovery Wastewater via a Novel Electro-Coagulation Method

    Wei Cui1,2,*, Zhilun Yan1,2, Zhi Tang1,2, Mengyao Xu1,2, Jian Tian1,2, Chengyi Shen1,2

    FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.1, pp. 51-60, 2023, DOI:10.32604/fdmp.2023.021499

    Abstract At present, methods for treating tertiary oil recovery wastewater via electro-coagulation are still in their early stage of development. In this study, a device for electro-coagulation wastewater treatment was built and tested in an oil field. The effects that the initial pH value, electrode type, and connection mode have on the coagulation and separation effect were assessed by measuring the mass fraction and turbidity of oil. The results have shown that when the electro-coagulation method is used, the effectiveness of the treatment can be significantly increased in neutral pH conditions (pH = 7), in acidic conditions, and More >

  • Open Access


    Recycling of Mud Derived from Backwash Wastewater Coagulation as Magnetic Sodalite Sphere for Zn2+Adsorption

    Suiyi Zhu1, Manhong Ji1, Hongbin Yu1,*, Zhan Qu1, Jiakuan Yang2, Mingxin Huo1, Yi Wang1

    Journal of Renewable Materials, Vol.9, No.9, pp. 1599-1607, 2021, DOI:10.32604/jrm.2021.015189


    Herein, we reported a method to prepare magnetic sodalite sphere by using the mud from backwash wastewater after polyaluminum chloride (PAC) coagulation. The results showed that approximately 100% of Fe in the wastewater was precipitated as flocculent iron mud (FM) by adding PAC. FM was converted to spherical magnetic sodalite (FMP) with a diameter of 3 μm via a facile alkali hydrothermal method without adding Al/Si resources or reductant. The product FMP had the saturated magnetization of 10.9 emu g−1 and high Zn2+ adsorption capacity of 50.6 mg g−1. Without coagulation with PAC, the removal rate of

    More > Graphic Abstract

    Recycling of Mud Derived from Backwash Wastewater Coagulation as Magnetic Sodalite Sphere for Zn<sup>2+</sup>Adsorption

  • Open Access


    Kawasaki disease: Medical therapies

    Jane W. Newburger

    Congenital Heart Disease, Vol.12, No.5, pp. 641-643, 2017, DOI:10.1111/chd.12502

    Abstract Medical therapies in patients with Kawasaki disease (KD) are administered to reduce the prevalence of coronary aneurysms, reduce systemic inflammation, and prevent coronary thrombosis. All patients with acute KD should be treated with intravenous immunoglobulin (IVIG) 2 g/kg, generally administered over 10–12 hours. Aspirin has never been shown to prevent aneurysms, but is given for its anti-inflammatory and antipyretic effects until the patient has been afebrile for 2 days, then lowered to an antiplatelet dose. Adjunctive therapy with a longer course of corticosteroids, together with IVIG and aspirin, may be considered for primary treatment in More >

  • Open Access


    Anticoagulation practices in adults with congenital heart disease and atrial arrhythmias in Switzerland

    Ketina Arslani1*, Lukas Notz1*, Marzena Zurek1, Matthias Greutmann2, Markus Schwerzmann3, Judith Bouchardy4, Reto Engel5, Christine Attenhofer Jost6, Daniel Tobler1

    Congenital Heart Disease, Vol.13, No.5, pp. 678-684, 2018, DOI:10.1111/chd.12627

    Abstract Background: In adults with congenital heart disease (CHD) and atrial arrhythmias, recommendations for thromboprophylaxis are vague and evidence is lacking. We aimed to identify factors that influence decision-making in daily practice.
    Methods: From the Swiss Adult Congenital HEart disease Registry (SACHER) we identified 241 patients with either atrial fibrillation (Afib) or atrial flutter/intraatrial reentrant tachycardia (Aflut/ IART). The mode of anticoagulation was reviewed. Logistic regression models were used to assess factors that were associated with oral anticoagulation therapy.
    Results: Compared with patients with Aflut/IART, patients with Afib were older (51 ± 16.1 vs 37 ± 16 years, P… More >

  • Open Access


    Low molecular weight heparin as an anticoagulation strategy for left-sided ablation procedures

    Karen Hinsley, Margaret Evans-Langhorst, Courtney Porter, Stephanie Chandler, Christina VanderPluym, John Triedman, Vassilios J. Bezzerides

    Congenital Heart Disease, Vol.13, No.2, pp. 222-225, 2018, DOI:10.1111/chd.12551

    Abstract Objective: This quality improvement study was implemented to demonstrate consistent and reliable post procedure anticoagulation for patients undergoing left-sided ablations. We evaluated the safety and efficacy of anticoagulation practice during a transition from anticoagulation with overnight infusion of unfractionated heparin to a single subcutaneous injection of low molecular weight heparin.
    Methods: Outcomes for patients who received unfractionated heparin from January 2014 to October 2014, were compared with outcomes of patients who received low molecular weight heparin from October 2014 to October 2015. Complications prepractice and postpractice change were documented and compared to establish confidence in the practice… More >

  • Open Access


    Heparin-induced thrombocytopenia complicating children after the Fontan procedure: Single-center experience and review of the literature

    Uri Pollak1,2,3, David Mishaly3,4, Gili Kenet3,5, Amir Vardi1,3

    Congenital Heart Disease, Vol.13, No.1, pp. 16-25, 2018, DOI:10.1111/chd.12557

    Abstract Heparin-induced thrombocytopenia (HIT) is a life-threatening complication of heparin therapy. The risk for HIT correlates with the cumulative dosage of heparin exposure. In Fontan patients, recurrent systemic anticoagulation, traditionally with heparin, is used to alleviate the thrombotic complications that may occur postoperatively when the venous pressure rises and the systemic venous flow into the pulmonary arteries becomes sluggish, putting them at increased risk. As a pressure gradient-dependent circulation, elevation in systemic venous pressure, most often by venous thrombosis, contributes to circuit failure. Therefore, when HIT complicates patients after the Fontan procedure, it is associated with More >

  • Open Access


    Microspheres Modified with the Heparin Increasing the Length of Molecular Linker to Better Capture the Endotoxin

    Qi Dang1, Chun-Gong Li1, Xin-Xin Jin1, Ya-Jin Zhao1, Xiang Wang1,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 146-146, 2019, DOI:10.32604/mcb.2019.07074

    Abstract Endotoxin is a a very powerful and toxic inflammatory stimulator usually leading to the sepsis occurred. In order to remove endotoxin better through hemoperfusion, it is a pretty choice to increase the length of molecular linker on adsorbents. In this study, we chose the heparin as a molecular linker because of its being anticoagulant linear polysaccharide. Heparin as a linker was covalently immobilized on the chloromethylated polystyrene microspheres (Ps) and then connected with L-phenylalanine (Phe) forming the Ps-Hep-Phe structure to adsorbed endotoxin better. The property of microspheres was characterized by Fourier transform infrared spectroscopy, X-ray More >

  • Open Access


    Supramolecular Design of Cellulose Hydrogel Beads

    Poonam Trivedi1, Jens Schaller2, Jan Gustafsson1, Pedro Fardim1,3*

    Journal of Renewable Materials, Vol.5, No.5, pp. 400-409, 2017, DOI:10.7569/JRM.2017.634143

    Abstract In the present study, we report the supramolecular design of cellulose-sulfonate hydrogel beads by blending water soluble sodium cellulose ethyl sulfonate (CES) with the pretreated cellulose in sodium hydroxide-ureawater solvent system at −6 °C followed by coagulation in the 2M sulfuric acid system. The increasing of CES amount from 10% to 90% had a substantial effect on the viscosity and storage (G′) and loss (G″) moduli of the blended solutions. The CES concentration up to 50% in blends led to the formation of physically stable hydrogels after coagulation in acidic medium at pH-1 and showed… More >

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