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  • Open Access

    ARTICLE

    2,4-D Hyper Accumulation Induced Cellular Responses of Azolla pinnata R. Br. to Sustain Herbicidal Stress

    Arnab Kumar De, Arijit Ghosh, Debabrata Dolui, Indraneel Saha, Malay Kumar Adak*

    Phyton-International Journal of Experimental Botany, Vol.89, No.4, pp. 999-1017, 2020, DOI:10.32604/phyton.2020.010828

    Abstract In the present experiment with ongoing concentration (0 µM, 100 µM, 250 µM, 500 µM and 1000 µM) of 2,4-D, the responses of Azolla pinnata R.Br. was evaluated based on cellular functions. Initially, plants were significantly tolerated up to 1000 µM of 2,4-D with its survival. This was accompanied by a steady decline of indole acetic acid (IAA) concentration in tissues with 78.8% over the control. Membrane bound H+ -ATPase activity was over expressed within a range of 1.14 to 1.25 folds with activator (KCl) and decreased within a range of 57.3 to 74.6% in response to inhibitor (Vanadate) application.… More >

  • Open Access

    ARTICLE

    DNA damage-induced by sodium flouride (NaF) and the effect of cholicalciferol

    VEYSEL YÜKSEK1,*, SEMIHA DEDE2, AYŞE USTA3, SEDAT ÇETIN2, MEHMET TAŞPINAR4

    BIOCELL, Vol.44, No.2, pp. 263-268, 2020, DOI:10.32604/biocell.2020.09172

    Abstract It is known that the high electronegativity of fluorine affects various soft tissues, especially the bone structure in organisms. Of these tissues are the kidneys, which play an important role in the excretion of fluoride from the body. Fluoride affects many cellular mechanisms. One of these effects is DNA damage. Our study aimed to investigate the likely protective effect of cholecalciferol (vitamin D3) on genomic DNA damage-induced NaF depending on concentration and time. The IC25 and IC50 values of NaF for 3, 12 and 24 h and optimum dose of increase in proliferation to vitamin D3 through MTT assay in… More >

  • Open Access

    ARTICLE

    Genotoxic effect of Physalis angulata L. (Solanaceae) extract on human lymphocytes treated in vitro

    RAQUEL ALVES DOS SANTOS1, TERESINHA ROSA CABRAL2, ISABEL ROSA CABRAL2, LUSÂNIA MARIA GREGGI ANTUNES3,4, CRISTIANE PONTES ANDRADE3, PLÍNIO CERQUEIRA DOS SANTOS CARDOSO1, MARCELO DE OLIVEIRA BAHIA2, CLAUDIA PESSOA5, JOSÉ LUIS MARTINS DO NASCIMENTO2, ROMMEL RODRÍGUEZ BURBANO2, CATARINA SATIE TAKAHASHI1,6

    BIOCELL, Vol.32, No.2, pp. 195-200, 2008, DOI:10.32604/biocell.2008.32.195

    Abstract Physalis angulata L (Solanaceae) is a medicinal plant from North of Brazil, whose different extracts and infusions are commonly used in the popular medicine for the treatment of malaria, asthma, hepatitis, dermatitis and rheumatism. However, the genotoxic effects of P. angulata on human cells is not well known. The main purpose of the present study was to evaluate the in vitro genotoxic effects of aqueous extract of P. angulata using the comet assay and the micronucleus assay in human lymphocytes provided from 6 healthy donors. Treatments with P. angulata extracts were performed in vitro in order to access the extent… More >

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