Chih-Yin Chien^1,2, Tsae-Jyy Wang¹, Pei-Hung Liao¹, Ying-Hsiang Lee^3,4,5,*, Wei-Sho Ho^6,7,*

Congenital Heart Disease, Vol.20, No.5, pp. 601-612, 2025, DOI:10.32604/chd.2025.072431 - 30 November 2025

Abstract Background: Cardiac implantable electronic devices (CIEDs) are essential for preventing sudden cardiac death in patients with cardiovascular diseases, but implantation procedures carry risks of complications such as infection, hematoma, and bleeding, with incidence rates of 3–4%. Previous studies have examined individual risk factors separately, but integrated predictive models are lacking. We compared the predictive performance and interpretability of artificial neural network (ANN) and logistic regression models to evaluate their respective strengths in clinical risk assessment. Methods: This retrospective study analyzed data from 180 patients who underwent cardiac implantable electronic device (CIED) implantation in Taiwan between 2017… More >

Raidizon Mercedes, Eric Eidelman, Michael Mawhorter, Max Yudovich, Alireza Aminsharifi^*

Canadian Journal of Urology, Vol.32, No.5, pp. 515-520, 2025, DOI:10.32604/cju.2025.067973 - 30 October 2025

Abstract Background: Spontaneous rupture of the urinary bladder (SRUB) is a rare condition characterized by bladder rupture without any trauma or previous instrumentation. Diagnosing SRUB can be challenging, leading to potential delays in treatment and significant morbidity. Case description: We present a case of a 75-year-old male with a complex medical history, including atrial fibrillation, systemic lupus erythematosus, antiphospholipid syndrome, and chronic anticoagulation, who developed sudden onset gross hematuria and abdominal pain following bilateral internal iliac artery angioembolization for a spontaneous pelvic hematoma in the setting of supratherapeutic anticoagulation. Extraperitoneal bladder perforation was confirmed by CT cystogram.… More >

Stamatios Katsimperis^1,*, Lazaros Tzelves¹, Georgios Feretzakis², Themistoklis Bellos¹, Panagiotis Deligiannis¹, Andreas Skolarikos¹, Athanasios Papatsoris¹, Iraklis Mitsogiannis¹

Canadian Journal of Urology, Vol.32, No.4, pp. 271-282, 2025, DOI:10.32604/cju.2025.066395 - 29 August 2025

Abstract Background: Accurate complication reporting in endourology remains challenging, with the Clavien-Dindo Classification and Comprehensive Complication Index being the most commonly used systems. This study aimed to compare surgical outcomes and complication reporting in ureterolithotripsy (URL), percutaneous nephrolithotomy (PCNL), and extracorporeal shock wave lithotripsy (ESWL) using both systems. Methods: This prospective, single-center, non-interventional study included 473 patients undergoing URL, PCNL, or ESWL from October 2022 to October 2024. Demographic, stone-related, and procedural variables were recorded. Complications were classified using the CDC, and cumulative morbidity was assessed using CCI. Statistical analyses, including univariate and multivariate regression, were… More >

Brian Gilmartin^*, Sorcha O’Meara, Michelle Horan, Frank T. D’Arcy, Catherine M. Dowling

Canadian Journal of Urology, Vol.32, No.4, pp. 293-298, 2025, DOI:10.32604/cju.2025.065805 - 29 August 2025

Abstract Background: Radiation cystitis is a well-known complication resulting from radiotherapy for pelvic malignancies. It remains a challenging condition to treat and is associated with significant morbidity for patients. We aimed to establish the economic cost burden of presentations and investigations associated with radiation cystitis over a two-year period to a tertiary referral hospital in Ireland. Materials and Methods: A retrospective review of patient charts was performed for radiation cystitis-related presentations and investigations over 24 months. Costs were estimated in consultation with the hospital finance department and using Health Service Executive data on diagnostic-related groups and average More >

Ryan Daigle¹, Ilene Staff², Joseph Tortora², Tara McLaughlin Proto^3,*, Kevin Pinto³, Rosa Negron², Jonathan Earle⁴, Joseph Wagner,³

Canadian Journal of Urology, Vol.32, No.3, pp. 189-198, 2025, DOI:10.32604/cju.2025.063773 - 27 June 2025

Abstract Introduction: We examined the pathology and safety outcomes associated with the extent of pelvic lymph node dissection in patients with high-risk prostate cancer undergoing radical prostatectomy. Materials and Methods: We retrospectively identified men with prostate cancer who underwent robot-assisted radical prostatectomy with pelvic lymph node dissection between May 2016 and September 2021. Cases were categorized using Current Procedural Terminology (CPT) codes (38571) for extended lymph node dissection and super-extended lymph node dissection (38572). Using logistic regression, we compared the groups on a number of factors, including recurrence. Results: Super-extended lymph node dissection had significantly higher median… More >

Matthew Buell, Brian Hu

Canadian Journal of Urology, Vol.31, No.5, pp. 12026-12029, 2024

Abstract Radical cystectomy is a preferred treatment for muscle invasive bladder cancer. Despite known complications, rapid onset, severe hyperkalemia necessitating abortion of surgery has not been reported. In this case report, a patient with end stage renal disease (ESRD) undergoing attempted cystectomy developed severe intraoperative hyperkalemia and acidosis that led to abortion of surgery and transfer to the medical intensive care unit for emergent hemodialysis. The multifactorial etiology was related to respiratory acidosis, ESRD, patient positioning, clipping of ureters, and body habitus, as well as an idiopathic element. Knowledge of hyperkalemia etiologies can assist in diagnosis More >

Hayatu Uma^1,*, Abdulaziz Aminu¹, Raghu Cherukupalli², Femi Akindotun Akintomide¹, Abdul Habu³, Aisha Aminu Lawal¹, Adamu Mohammad¹

Congenital Heart Disease, Vol.19, No.6, pp. 635-645, 2024, DOI:10.32604/chd.2025.056641 - 27 January 2025

Abstract Laubry-Pezzi syndrome (L-PS) is a rare congenital heart disease characterized by a ventricular septal defect (VSD) and aortic valve prolapse. These cardiac lesions predispose individuals to infective endocarditis (IE), a life-threatening complication, especially in resource-constrained settings. A 17-year-old male presented with a three-week history of fever and headache, and a one-week history of abdominal pain, vomiting, and diarrhea. On presentation, he appeared toxic, was febrile, tachypneic, tachycardic, and blood pressure of 120/30 mmHg, and heart sounds were S1, S2. Abdominal examination revealed generalized tenderness. A provisional diagnosis of typhoid sepsis with intestinal perforation was considered.… More >

Jonathan S. Taylor-Fishwick^1,*, Nicholas Holzemer², Brandon Middlemist³, Vivian Duarte³, Kaitlin E. Olson⁴, Johannes C. von Alvensleben⁵, Megan SooHoo⁶, Amber Khanna⁷

Congenital Heart Disease, Vol.19, No.5, pp. 457-472, 2024, DOI:10.32604/chd.2024.057151 - 31 December 2024

Abstract Background: Post-operative atrial fibrillation (POAF) frequently occurs after cardiac surgery. Although adult congenital heart disease (ACHD) patients have higher rates of arrhythmia than the general population, there is scant literature on POAF in ACHD patients. Objectives: Identify key risk factors associated with post-operative atrial fibrillation and evaluate the short- and mid-term significance of developing POAF. Methods: A retrospective cohort study was conducted of ACHD patients from 2013–2021 at the University of Colorado Hospital and Children’s Hospital of Colorado. The institutional Society of Thoracic Surgeons (STS) surgical registry was used to identify patients ≥18-year-old with congenital heart… More >

Gustavo Cruz^1,*, Santiago Pedroza², Juan F. Vélez³, Jessica Largo², Juan F. Tejada⁴, Jorge H. Mejía-Mantilla⁵

Congenital Heart Disease, Vol.19, No.2, pp. 207-218, 2024, DOI:10.32604/chd.2024.044244 - 16 May 2024

Abstract Background: Failure to rescue has been an effective quality metric in congenital heart surgery. Conversely, morbidity and mortality depend greatly on non-modifiable individual factors and have a weak correlation with better-quality performance. We aim to measure the complications, mortality, and risk factors in pediatric patients undergoing congenital heart surgery in a high-complexity institution located in a middle-income country and compare it with other institutions that have conducted a similar study. Methods: A retrospective observational study was conducted in a high-complexity service provider institution, in Cali, Colombia. All pediatric patients undergoing any congenital heart surgery between… More >

David-Dan Nguyen^1,*, Massine Fellouah^2,*, Anna-Lisa V. Nguyen³, David-Christian Kazu⁴, Isabel Baltzan⁵, Muhieddine Labban⁶, Shubha De⁷, Kevin C. Zorn⁸, Bilal Chughtai⁹, Dean S. Elterman¹, Quoc-Dien Trinh⁶, Naeem Bhojani⁸

Canadian Journal of Urology, Vol.30, No.3, pp. 11546-11550, 2023

Abstract Introduction: 5α-reductase inhibitors (5ARI) are commonly prescribed medications. There is ongoing controversy about the adverse events of these medications. The aim of this study is to characterize lawsuits in Canada involving medical complications of 5ARIs use.
Materials and methods: Legal cases were queried from CanLII. Cases were included if they involved a party taking a 5ARI who alleged an adverse event. Relevant full cases were retained, and pertinent characteristics were extracted with the help of a legal expert.
Results: Our deduplicated search yielded 67 unique legal documents from December 2013 to February 2019. Twelve of these documents met… More >