Yu Zhu1*, Yong Chen1*, Yu Feng2, Di Yu1, Xuming Mo1
Congenital Heart Disease, Vol.13, No.2, pp. 271-281, 2018, DOI:10.1111/chd.12567
Abstract We conducted this meta-analysis to address the open question of a possible association between
maternal body mass index (BMI) and congenital heart defects (CHDs) in infants. We conducted a
comprehensive computerized search of PubMed, Web of Science, Medline, and Embase databased
(January 1980 through August 2017). We assessed the association between maternal BMI and the
risk for congenital heart defects in their offspring. Study-specific relative risk estimates were polled
according to random-effect or fixed-effect models. From 2567 citations, a total of 13 case-control
studies and 4 cohort studies were selected for a meta-analysis, including more than 1 150 000
cases.… More >
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