Safwat A. Aly1, David Zurakowski2, Penny Glass3, Kami Skurow-Todd4, Richard A. Jonas5, Mary T. Donofrio4
Congenital Heart Disease, Vol.12, No.2, pp. 188-195, 2017, DOI:10.1111/chd.12426
Abstract Importance: There are no well-established noninvasive biomarkers for identifying patients at risk
for poor outcome after surgery for congenital heart disease. Few studies have assessed prognostic
accuracy of cerebral tissue oxygenation index (cTOI) measured by near infrared spectroscopy
(NIRS).
Objective: To assess the utility of noninvasive NIRS monitoring as a predictor of outcomes after
neonatal cardiac surgery through measurement of cTOI. To examine the utility of noninvasive
NIRS monitoring in combination with lactate concentration and inotropic score in prediction of
outcomes after neonatal cardiac surgery.
Design: Prospective longitudinal cohort study.
Setting: Operating room and cardiac intensive care unit, Children’s National… More >
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