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    ARTICLE

    A Continuum Model for Pressure-Flow Relationship in Human Pulmonary Circulation

    Wei Huang∗,†, Qinlian Zhou†,‡, Jian Gao, R. T. Yen‡,§,¶

    Molecular & Cellular Biomechanics, Vol.8, No.2, pp. 105-122, 2011, DOI:10.3970/mcb.2011.008.105

    Abstract A continuum model was introduced to analyze the pressure-flow relationship for steady flow in human pulmonary circulation. The continuum approach was based on the principles of continuum mechanics in conjunction with detailed measurement of vascular geometry, vascular elasticity and blood rheology. The pulmonary arteries and veins were considered as elastic tubes and the "fifth-power law" was used to describe the pressure-flow relationship. For pulmonary capillaries, the "sheet-flow" theory was employed and the pressure-flow relationship was represented by the "fourth-power law". In this paper, the pressure-flow relationship for the whole pulmonary circulation and the longitudinal pressure distribution along the streamlines were… More >

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