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  • Open Access

    ARTICLE

    Balanced GHM Mutiwavelet Transform Based Contrast Enhancement Technique for Dark Images Using Dynamic Stochastic Resonance

    S. Deivalakshmi*, P. Palanisamy1, X. Z. Gao2

    Intelligent Automation & Soft Computing, Vol.25, No.3, pp. 459-471, 2019, DOI:10.31209/2018.100000001

    Abstract The main aim of this paper is to propose a new technique for enhancing the contrast of dark images using Dynamic Stochastic Resonance (DSR) and Multi Wavelet Transform (MWT), which is computationally more efficient than the conventional methods. In the work, for enhancing the contrast of dark images, the intrinsic noise (darkness) of dark images has been used. The proposed MWT-based DSR scheme (MWT-DSR) can yield better performances in terms of visual information and color preservation than already reported techniques. The desired output response is validated by the Relative Contrast Enhancement Factor (F), Perceptual Quality More >

  • Open Access

    ARTICLE

    Impact of contrast exposure from computed tomography angiography on acute kidney injury after neonatal cardiopulmonary bypass surgery

    Waldemar F. Carlo1, Steven T. Clark2, Santiago Borasino3, Jeffrey A. Alten3

    Congenital Heart Disease, Vol.12, No.4, pp. 540-545, 2017, DOI:10.1111/chd.12482

    Abstract Objective: Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass (CBP) for cardiac surgery in neonates. It is unclear if exposure to computed tomography angiography (CTA) in the preoperative period increases the risk of AKI. We hypothesized a short interval between CTA and CPB surgery would be associated with higher rates of AKI in infants.
    Design: In this single center retrospective review of patients between 2012 and 2015, neonates less than one month old were analyzed if they had CTA prior to cardiac surgery with CPB. Baseline, demographic, fluid balance, and laboratory data was analyzed.… More >

  • Open Access

    ARTICLE

    Exercise testing and spirometry as predictors of mortality in congenital heart disease: Contrasting Fontan physiology with repaired tetralogy of Fallot

    Keri M. Shafer1,2, Alexander R. Opotowsky1,2, Jonathan Rhodes1

    Congenital Heart Disease, Vol.13, No.6, pp. 903-910, 2018, DOI:10.1111/chd.12661

    Abstract Objective: Risk prediction using cardiopulmonary exercise testing (CPET) in complex congenital heart disease tends to either focus on single diagnoses or complete cohorts. We aimed to evaluate patients with two distinct anatomies cared for at a single institution over the same time period to determine CPET variables associated with mortality.
    Design: All Fontan and tetralogy of Fallot (TOF) subjects with CPET between November 1, 2002 and December 31, 2014 and subsequently died were identified (cases). Cases were matched 1:3 to controls with similar age, underlying anatomy and timing of exercise test.
    Results: Of the 42 cases, 27 had… More >

  • Open Access

    ARTICLE

    Evaluation of systemic microvascular reactivity in adults with congenital heart disease

    Pablo Marino1,2, Gabriella de Oliveira Lopes1,3, Juliana Pereira Borges3, Maria Carolina Terra Cola1, Daniel Arkader Kopiler1, Eduardo Tibirica1

    Congenital Heart Disease, Vol.13, No.6, pp. 978-987, 2018, DOI:10.1111/chd.12660

    Abstract Objective: Adults with congenital heart disease share some features with those with chronic heart failure. Although microvascular endothelial dysfunction has been de‐ scribed in chronic heart failure, evaluation of the microcirculation in adults with con‐ genital heart disease is lacking. The present study aimed to investigate systemic microvascular reactivity in adults with congenital heart disease.
    Interventions: The patients initially underwent cardiopulmonary exercise testing. Then, the cutaneous microvascular reactivity was evaluated in these patients using a laser speckle contrast imaging system coupled with skin iontophoresis of endothelial‐de‐ pendent (acetylcholine) or ‐independent (sodium nitroprusside) vasodilators and pos‐ tocclusive reactive… More >

  • Open Access

    ARTICLE

    Kidney injury biomarkers after cardiac angiography in children with congenital heart disease

    Masashi Nishida, Shingo Kubo, Yuma Morishita, Kosuke Nishikawa, Kazuyuki Ikeda, Toshiyuki Itoi, Hajime Hosoi

    Congenital Heart Disease, Vol.14, No.6, pp. 1087-1093, 2019, DOI:10.1111/chd.12853

    Abstract Objective: This study aims to investigate the changes in renal function and levels of urinary biomarkers before and after cardiac angiography in children with congenital heart disease (CHD).
    Setting: Children with CHD are at a risk for kidney injury during contrast exposure in cardiac angiography.
    Outcome Measures: We measured urinary protein, albumin, N‐acetyl‐β‐D‐glucosaminidase (NAG), β2‐microglobulin (BMG), and liver‐type fatty acid‐binding protein (L‐FABP) levels, as well as serum creatinine and cystatin C levels, before and after cardiac angiography in 33 children with CHD.
    Results: No significant decrease was noted in either the creatinine‐based or cystatin C‐based estimated glomerular filtration rate… More >

  • Open Access

    ARTICLE

    A General Framework of Reversible Data Hiding with Controlled Contrast Enhancement

    Shaowei Weng1, 2, *, Yiyun Liu1, Yunqing Shi3, Bo Ou4, Chunyu Zhang5, Cuiping Wang6

    CMC-Computers, Materials & Continua, Vol.62, No.1, pp. 157-177, 2020, DOI:10.32604/cmc.2020.05681

    Abstract This paper proposes a two-step general framework for reversible data hiding (RDH) schemes with controllable contrast enhancement. The first step aims at preserving visual perception as much as possible on the basis of achieving high embedding capacity (EC), while the second step is used for increasing image contrast. In the second step, some peak-pairs are utilized so that the histogram of pixel values is modified to perform histogram equalization (HE), which would lead to the image contrast enhancement. However, for HE, the utilization of some peak-pairs easily leads to over-enhanced image contrast when a large… More >

  • Open Access

    ARTICLE

    Association Analysis of the Growth of Black Poplar (Populus Nigra L.) Under Contrasting Nitrogen Levels

    Xihua Liu1, Changjun Ding2, Xiaohua Su2,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.4, pp. 425-433, 2019, DOI:10.32604/phyton.2019.08285

    Abstract The European black poplar (Populus nigra L.) has been used as a germplasm resource for the breeding of new poplar varieties around the world. The identification and screening of its high nitrogen use efficiency genotypes could enable the breeding of new resource-efficient poplar varieties. The accessions were screened using MALDI-TOF MS genotyping technology for ammonium transporter (AMT) and nitrate transporters (NRT) genes against phenotypic data for seedling height and ground diameter traits, in both low and high nitrogen environments. Allele re-sequencing of seven genes related to root development was carried out using the minisequencing method. By cluster… More >

  • Open Access

    ARTICLE

    Brief Note: Influence of 2-methoxyestradiol on MCF-7 cells: An improved differential interference contrasting technique and Bcl-2 and Bax protein expression levels

    ANNIE JOUBERT1*, SUMARI MARAIS1, CHRISTINE MARITZ2

    BIOCELL, Vol.33, No.1, pp. 67-70, 2009, DOI:10.32604/biocell.2009.33.067

    Abstract Proteins of the B-cell lymphoma 2 family are crucial for the regulation of apoptosis. B-cell lymphoma 2-associated X is a pro-apoptotic protein, while B-cell lymphoma 2 protein opposes apoptosis. The influence of 1 μM 2-methoxyestradiol was investigated on the expression levels of these two proteins in MCF-7 cells. 2-Methoxyestradiol exposure did not influence B-cell lymphoma 2 protein expression levels after 24 h of exposure. In contrast, B-cell lymphoma 2-associated X protein levels were significantly reduced. An improved differential interference contrasting technique revealed compromised cell density and the presence of a mitotic block in exposed cells. More >

  • Open Access

    ABSTRACT

    Comparison of Aortic Flow Patterns in Patients with and without Aortic Valve Disease: Hemodynamic Simulation Based on PC-MRI and CTA Data

    Lijian Xu1,2, Lekang Yin3, Fuyou Liang1,2,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 71-72, 2019, DOI:10.32604/mcb.2019.05741

    Abstract Recent studies have revealed that aortic valve diseases are associated with the increased incidence of the aortopathy development. However, the influence of aortic valve diseases on aortic hemodynamics remains unclear. The purpose of this study was therefore to investigate the hemodynamic differences in patients with and without aortic valve disease through patient-specific simulations performed on two aorta models (BAV with severe stenosis vs. normal tricuspid aortic valve (TAV)). Realistic geometries and boundary conditions were obtained from computed tomography angiography (CTA) and phase-contrast magnetic resonance imaging (PC-MRI) measurements, respectively. In addition, 4D-MRI were performed to validate More >

  • Open Access

    ABSTRACT

    Automated Segmentation of Atherosclerotic Plaque Using Bayes Classifier for Multi-Contrast In Vivo and Ex Vivo MR Images

    Xueying Huang1, Chun Yang2, Jie Zheng3, Pamela K. Woodard3, Dalin Tang1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.1, No.1, pp. 29-34, 2007, DOI:10.3970/icces.2007.001.029

    Abstract Atherosclerotic plaques may rupture without warning and cause acute cardiovascular syndromes such as heart attack and stroke. Accurate identification of plaque components will improve the accuracy and reliability of computational models. In this article, we present a segmentation method using a cluster analysis technique to quantify and classify plaque components from magnetic resonance images (MRI). 3D in vivo and ex vivo multi-contrast (T1-, proton density-, and T2-weighted) MR Images were acquired from a patient of cardiovascular disease. Normal distribution Bayes classifier was performed on ex vivo and in vivo MR Images respectively. The resulting segmentation More >

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