Haoliang Zhang1,*, Xiaowei Xing2, Yang Liu1, Shuangli Li1, Weiyuan Li3
Oncologie, Vol.22, No.2, pp. 107-116, 2020, DOI:10.32604/oncologie.2020.012494
Abstract Lung cancer is the leading cause of death in cancer patients. Based on
a modular and comprehensive analysis method, it is intended to identify their
common pathogenesis. We downloaded data and analyzed differences in lung
adenocarcinoma samples, lung squamous cell carcinoma samples, and normal
samples. Co-expression analysis, enrichment analysis, and hypergeometric testing
were used to predict transcription factors, ncRNAs, and retrospective target genes.
We get 4596 differentially expressed genes in common differences in high
multiples and clustered into 14 modules dysfunction. The 14 genes (including
DOK2, COL5A1, and TSPAN8) have the highest connectivity in the dysfunction
module and are identified… More >
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