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    ARTICLE

    Computer Simulations of Atherosclerotic Plaque Growth in Coronary Arteries

    Biyue Liu, Dalin Tang

    Molecular & Cellular Biomechanics, Vol.7, No.4, pp. 193-202, 2010, DOI:10.3970/mcb.2010.007.193

    Abstract A three dimensional mathematical model with a linear plaque growth function was developed to investigate the geometrical adaptation of atherosclerotic plaques in coronary arteries and study the influences of flow wall shear stress (WSS), blood viscosity and the inlet flow rate on the growth of atherosclerotic plaques using computational plaque growth simulations. The simulation results indicated that the plaque wall thickness at the neck of the stenosis increased at a decreasing rate in the atherosclerosis progression. The simulation results also showed a strong dependence of the plaque wall thickness increase on the blood viscosity and the inlet flow rate. The… More >

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