Ricky Martinez†, Hai-Chao Han‡
Molecular & Cellular Biomechanics, Vol.9, No.1, pp. 55-76, 2012, DOI:10.3970/mcb.2012.009.055
Abstract The stability of arteries is essential to normal arterial functions and loss of stability can lead to arterial tortuosity and kinking. Collagen is a main extracellular matrix component that modulates the mechanical properties of arteries and collagen degradation at pathological conditions weakens the mechanical strength of arteries. However, the effects of collagen degradation on the mechanical stability of arteries are unclear. The objective of this study was to investigate the effects of collagen degradation on the critical buckling pressure of arteries. Arterial specimens were subjected to pressurized inflation testing and fitted with nonlinear thick-walled cylindrical model equations to determine their… More >
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