Peter Bak1, Cristel S. Hjortshøj2, Peter Gæde3, Lars Idorn4, Lars Søndergaard2, Annette S. Jensen2
Congenital Heart Disease, Vol.13, No.2, pp. 263-270, 2018, DOI:10.1111/chd.12565
Abstract Objective: Cyanotic congenital heart disease is a systemic disease, with effects on multiple organ
systems. A high prevalence of subclinical hypothyroidism (SCH) has been reported in a small cohort
of cyanotic congenital heart disease patients. Subclinical hypothyroidism has been associated with
various adverse cardiovascular effects, as well as an increased risk of progression to overt hypothyroidism. The aim of this study was to examine the prevalence of SCH in cyanotic congenital
heart disease patients, consider possible etiologies, and evaluate thyroid function over time.
Methods: First, 90 clinically stable cyanotic congenital heart disease patients were examined with
blood samples (thyroid-stimulating hormone,… More >
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