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    META-ANALYSIS

    The Effect of Carnitine Supplementation on Left Ventricular Function: Lessons from Current Evidence and Insights for Future Studies

    Rohit S. Loomba1,2, Enrique G. Villarreal3,*, Riddhi Patel1, Samantha Udarbe1, Vincent Dorsey1, Kristen Nelson-McMillan1,4, Saul Flores5,6

    Congenital Heart Disease, Vol.15, No.6, pp. 447-455, 2020, DOI:10.32604/CHD.2020.012927

    Abstract Introduction: In children, data on the effects on carnitine supplementation and myocardial function are limited. A few studies have investigated the relationship between serum carnitine levels in the setting of depressed cardiac function and have demonstrated possible benefits. As such, this systematic review and meta-analyses aimed to assess the effects carnitine supplementation on left ventricular function. Materials and Methods: A systematic review of the literature was performed to identify full text manuscripts in English. PubMed, EMBASE, and the Cochrane databases were queried. Studies were included with data from pediatric patients, that used carnitine supplementation and included preand post-carnitine data for… More >

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