Burcu BİTERGE SÜT1,*, Ayşe İKİNCİ KELEŞ2
Oncologie, Vol.22, No.3, pp. 147-154, 2020, DOI:10.32604/oncologie.2020.014449
Abstract Components of the protein synthesis machinery are subjected to
alterations in cancer cells. eEF1D gene, which lies within the frequently amplified
8q24 locus, is one of the subunits of the human eukaryotic elongation factor
complex. This study aimed to evaluate the prognostic and predictive significance
of eEF1D in breast cancer using in silico analysis tools. For this purpose, we
analyzed genomic alterations of the eEF1D gene using TCGA datasets via
cBioPortal. Histopathological analysis was performed on patient tissue images
obtained from cBioPortal and the Human Protein Atlas. Survival analysis was
carried out using the KM Plotter and the prediction of… More >
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