Alexander C. Egbe, William R. Miranda, Patricia A. Pellikka, Sorin V. Pislaru, Barry A. Borlaug, Srikanth Kothapalli, Sindhura Ananthaneni, Harigopal Sandhyavenu, Maria Najam, Mohamed Farouk Abdelsamid, Heidi M. Connolly
Congenital Heart Disease, Vol.14, No.4, pp. 657-664, 2019, DOI:10.1111/chd.12768
Abstract Background: We hypothesized that echocardiographic indices of right ventricular to
pulmonary artery (RV‐PA) coupling were comparable to cardiac magnetic resonance
imaging (CMRI)‐derived RV volumetric indices in predicting disease severity in
chronic pulmonary regurgitation (PR).
Methods: Patients with ≥ moderate PR (2003‐2015) with and without prior CMRI
scans were enrolled into the study cohort and validation cohort, respectively.
Endpoint was to determine the association between noninvasive RV‐PA coupling in‐
dices (tricuspid annular plane systolic excursion/right ventricular systolic pressure
[TAPSE/RVSP] and fractional area change [FAC]/RVSP ratio) and markers of disease
severity, and compared this association to that of CMRI‐derived RV volumetric indi‐… More >
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