Mengqi Li, Xiaodong Huang^*, Lifeng Wu

CMC-Computers, Materials & Continua, Vol.84, No.1, pp. 975-995, 2025, DOI:10.32604/cmc.2025.062621 - 09 June 2025

Abstract Micro-expressions, fleeting involuntary facial cues lasting under half a second, reveal genuine emotions and are valuable in clinical diagnosis and psychotherapy. Real-time recognition on resource-constrained embedded devices remains challenging, as current methods struggle to balance performance and efficiency. This study introduces a semi-lightweight multifunctional network that enhances real-time deployment and accuracy. Unlike prior simplistic feature fusion techniques, our novel multi-feature fusion strategy leverages temporal, spatial, and differential features to better capture dynamic changes. Enhanced by Residual Network (ResNet) architecture with channel and spatial attention mechanisms, the model improves feature representation while maintaining a lightweight design. More >

Oncology Research Editorial Office

Oncology Research, Vol.33, No.6, pp. 1509-1509, 2025, DOI:10.32604/or.2024.062048 - 29 May 2025

Abstract This article has no abstract. More >

MIAO YAN¹, DONGXUAN CHI², WEN WANG³, PEI PEI⁴, MIN XIE¹, SHUANGLING LI^1,*

BIOCELL, Vol.49, No.5, pp. 893-906, 2025, DOI:10.32604/biocell.2025.063622 - 27 May 2025

Abstract Background: Transcription factor Krüppel-like factor 3 (KLF3) may be involved in regulating inflammation and lymphocyte function. Immune dysfunction in sepsis involves both hyper-inflammation and immunosuppression. However, studies on T-lymphocyte KLF3 expression in sepsis are lacking. Methods: We induced sepsis in mice via cecal ligation and puncture (CLP), and their survival rate over 7 days was evaluated. To identify the immune status of these mice, we assessed their cytokine levels, organ damage scores, and splenic T-lymphocyte phenotype. Finally, T-lymphocyte KLF3 expression was detected through flow cytometry. Results: Over the 7 days of observation, septic mice demonstrated 64.7%… More >

Jiawei Shi^1,2,3,#, Zhen Wang^1,2,3,#, Ying Bai^1,2,3, Shiying Li^1,2,3, Xin Zhang^1,2,3, Tianshu Liu^1,2,3, Liu Hong^1,2,3, Li Cui^1,2,3, Yi Zhang^1,2,3, Jing Ma^1,2,3, Juanjuan Liu^1,2,3, Jing Zhang^1,2,3, Haiyan Cao^1,2,3,*, Jing Wang^1,2,3,*

Congenital Heart Disease, Vol.20, No.2, pp. 213-229, 2025, DOI:10.32604/chd.2025.064950 - 30 April 2025

Abstract Background: Tetralogy of Fallot (TOF), the predominant cyanotic congenital heart defect, arises from multifactorial gene-environment interactions disrupting cardiac developmental networks. This study investigated TOF-specific transcriptional alterations and identified high-confidence candidate genes. Methods: Based on GSE36761 transcriptome data, a weighted gene co-expression network analysis (WGCNA) and protein-protein interaction (PPI) network were conducted to identify TOF-related sub-network and Hub genes. The potential biological functions among these genes were revealed by enrichment analysis. Genetic, epigenetic and transcriptional alteration in the Hub genes were analyzed with leveraged public resources: a methylation dataset (GSE62629) and two single-cell datasets (EGAS00001003996 and GSE126128). Results:… More >

Yuxin Zhao, Zhanxiang Tan, Yuying Li, Kaiyue Zhang, Lili Guo^*, Xiaogai Hou^*

Phyton-International Journal of Experimental Botany, Vol.94, No.4, pp. 1159-1176, 2025, DOI:10.32604/phyton.2025.063737 - 30 April 2025

Abstract Receptor-like cytoplasmic kinases (RLCKs) play a crucial role in the physiological processes of plant growth and development and stress response. To elucidate the characteristics and functions of the PBL gene family in tree peonies, the whole genome identification of PBL family members in tree peonies was conducted using a bioinformatics approach based on the published Arabidopsis thaliana PBL protein sequence. A total of 51 PoPBL members were identified, which were distributed unevenly on five chromosomes in the tree peony. PoPBL proteins were localized in the nucleus, cytoplasm, chloroplasts, and mitochondria, with most members of the same clade… More >

Yuhang Li¹, Li Sun¹, Tao Wang¹, Bingjun Yu², Zhihong Gao³, Xiaochun Shu¹, Tengyue Yan¹, Weibing Zhuang^1,2,*, Zhong Wang^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.4, pp. 1211-1223, 2025, DOI:10.32604/phyton.2025.063647 - 30 April 2025

Abstract bHLH transcription factors, widely exist in various plants, and are vital for the growth and development of these plants. Among them, many have been implicated in anthocyanin biosynthesis across various plants. In the present study, a PdbHLH57 gene, belonging to the bHLH IIIf group, was characterized, which was isolated and cloned from the colored-leaf poplar ‘Zhongshancaiyun’ (ZSCY). The cDNA sequence of PdbHLH57 was 1887 base pairs, and the protein encoded by PdbHLH57 had 628 amino acids, the isoelectric point and molecular weight of which were 6.26 and 69.75 kDa, respectively. Through bioinformatics analysis, PdbHLH57 has been classified… More >

Zijian Liu¹, Yong Shi², Chuanqi Li¹, Xiliang Zhang^3,*, Jian Zhou¹, Manoj Khandelwal^4,*

CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.1, pp. 153-183, 2025, DOI:10.32604/cmes.2025.062426 - 11 April 2025

Abstract Given the growing concern over global warming and the critical role of carbon dioxide (CO₂) in this phenomenon, the study of CO₂-induced alterations in coal strength has garnered significant attention due to its implications for carbon sequestration. A large number of experiments have proved that CO₂ interaction time (T), saturation pressure (P) and other parameters have significant effects on coal strength. However, accurate evaluation of CO₂-induced alterations in coal strength is still a difficult problem, so it is particularly important to establish accurate and efficient prediction models. This study explored the application of advanced machine learning (ML)… More >

Ran Li^1,#, Liuhong Chen^1,#, Yu Liu¹, Chunlei Zhao^1,2, Yanli Li^1,2, Guangzhou Ding^1,2,*

Phyton-International Journal of Experimental Botany, Vol.94, No.3, pp. 875-895, 2025, DOI:10.32604/phyton.2025.061550 - 31 March 2025

Abstract Mildew resistance locus O (MLO) proteins are extensively found in various plant species and are essential for multiple biological functions. The characterization and analysis of MLO genes have been conducted across numerous species. However, the functions and features of MLO genes inside sugar beet remain poorly understood. In the present research, we conducted a comprehensive analysis of the structural features of MLO genes, physicochemical characteristics of proteins, evolutionary connections, and expression profiles in sugar beet. A total of 13 BvMLO genes containing MLO structural domains were detected and renamed based on their locations on chromosomes within the sugar… More >

Xiaojian Chen^1,2,#, Zhujiang Dai^1,#, Qiang Wang³, Wei Chen¹, Yun Liu^1,*, Zhongchuan Wang^1,*

BIOCELL, Vol.49, No.3, pp. 503-518, 2025, DOI:10.32604/biocell.2025.059286 - 31 March 2025

Abstract Background: Nudix Hydrolase 21 (NUDT21) is crucial for the regulation of alternative polyadenylation, with its reduced expression frequently resulting in a shortened mRNA 3^′ untranslated region (UTR), thereby enhancing the protein levels of downstream genes. Although NUDT21 is widely recognized for its tumor-suppressive function in various cancers, its involvement in colorectal cancer (CRC) remains poorly understood. Methods: The expression of NUDT21 in CRC and adjacent normal tissues was analyzed through qPCR, Western blot, and immunohistochemistry (IHC). Additionally, we investigated the correlation between NUDT21 expression and patient prognosis. With Cell Counting Kit-8 assay and Transwell assay, we… More >

Oncology Research Editorial Office

Oncology Research, Vol.33, No.4, pp. 989-989, 2025, DOI:10.32604/or.2024.056912 - 19 March 2025

Abstract This article has no abstract. More >