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    Near Future Perspective of ESBL-Producing Klebsiella pneumoniae Strains Using Mathematical Modeling

    Cemile Bagkur1,*, Emrah Guler2,3, Bilgen Kaymakamzade4,5, Evren Hincal4,5, Kaya Suer6

    CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.1, pp. 111-132, 2022, DOI:10.32604/cmes.2022.016957

    Abstract While antibiotic resistance is becoming increasingly serious today, there is almost no doubt that more challenging times await us in the future. Resistant microorganisms have increased in the past decades leading to limited treatment options, along with higher morbidity and mortality. Klebsiella pneumoniae is one of the significant microorganisms causing major public health problems by acquiring resistance to antibiotics and acting as an opportunistic pathogen of healthcare-associated infections. The production of extended spectrum beta-lactamases (ESBL) is one of the resistance mechanisms of K. pneumoniae against antibiotics. In this study, the future clinical situation of ESBL-producing K. pneumoniae was investigated in… More >

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