Ryan D. Byrne1, Angela J. Weingarten2, Daniel E. Clark2, Shi Huang3, Roman E. Perri4, Andrew E. Scanga4, Jonathan N. Menachem2, Larry W. Markham5, Benjamin P. Frischhertz2
Congenital Heart Disease, Vol.14, No.5, pp. 765-771, 2019, DOI:10.1111/chd.12820
Abstract Setting: Fontan‐associated liver disease universally affects adults with single ventricle heart disease. Chronic kidney disease is also highly prevalent in adult Fontan
patients. In this study, we evaluate the relationship of Fontan hemodynamics invasively and noninvasively with extra‐cardiac dysfunction as measured by MELD and
MELD‐XI.
Objective: We hypothesize that invasive and noninvasive measures of Fontan circuit congestion and ventricular dysfunction are associated with increased MELD and
MELD‐XI scores.
Design: Single‐center data from adults with Fontan palliation who had ongoing care,
including cardiac catheterization, were retrospectively collected. Hemodynamic data
from cardiac catheterization and echocardiographic assessment of ventricular and
atrioventricular valve function… More >
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