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    REVIEW

    Climate Change and Congenital Heart Disease: A Narrative Review

    Ethan Katznelson1, Matthew J. Navarro2, Su Yuan1, Dhurv S. Kazi3, Harsimran S. Singh1,*

    Congenital Heart Disease, Vol.19, No.6, pp. 627-634, 2024, DOI:10.32604/chd.2025.062309 - 27 January 2025

    Abstract Congenital Heart Disease (CHD) is the most common birth defect and a leading cause of infant morbidity and mortality worldwide. While genetic factors play a significant role in its development, up to 30% of CHD is associated with modifiable risk factors and external maternal exposures. Climate change, driven by increased atmospheric pollutants from fossil fuel combustion, leads to rising global temperatures and worsening air quality, which pose emerging threats to maternal and fetal health. This review explores the mechanisms by which environmental factors associated with climate change, specifically extreme heat and air pollution, may influence… More >

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